Micro-nano bionic artificial skin repair membrane

Abstract

The invention discloses a micro-nano bionic artificial skin repair membrane which comprises a base membrane, a support layer, an epidermal membrane and a separable surface membrane, wherein the base membrane, the support layer, the polyurethane epidermal membrane and the separable surface membrane are sequentially laminated from inside to outsid, the base membrane is a non-woven membrane formed byelectrostatic spinning and jet weaving of sericin, the diameter of the sericin electrostatic spinning ranges from 50 nm to 500 nm, the support layer is a non-woven layer formed by blending electrostatic spinning and spray weaving, the blended electrostatic spun fiber is a spiral fiber yarn formed by blending PLA and PCL, the diameter of the blended electrostatic spun fiber is 0.2-5 [mu]m, the epidermal membrane is a biodegradable polyurethane membrane and the separable surface membrane is formed by weaving polypropylene fibers. The micro-nano bionic artificial skin repair membrane is good inbiocompatibility, good in degradability and beneficial for replacing self-transplanted skin and promoting repairing of damaged skin.

Description

technical field [0001] The invention relates to the field of artificial functional membranes, in particular to a micro-nano bionic artificial skin repair membrane. Background technique [0002] Skin refers to the tissue on the surface of the body that covers the muscles. It is the largest organ in the human body and is mainly responsible for protecting the body, perspiration, and feeling cold, heat, and pressure. Skin covers the whole body, and it can protect various tissues and organs in the body from physical, mechanical, chemical and pathogenic microorganisms. Therefore, when the skin is damaged by trauma, burns, inflammation, etc., especially when a large area of ​​skin is seriously damaged, the wound should be protected immediately. [0003] For the repair of damaged skin, autologous skin grafting was mostly used before. The doctor removed a piece of intact skin from other parts of the patient's body and re-implanted the wounded site. However, this method not only caus...

AI Technical Summary

Problems solved by technology

[0003] For the repair of damaged skin, autologous skin transplantation was mostly used in the past. The doctor removed a piece of intact skin from other parts of the patient's body and re-implanted the wounded site. However, this method not only caused new wounds in the donor area In addition, there are differences in color, texture and function between the transplanted skin and the skin adjacent to the wound site

Later, some doctors used the method of cultivating dermal layer cells for skin repair, but because there is no complete skin tissue, the newly grown skin always has many defects.