High-precision erythrocyte sedimentation rate (ESR) temperature compensation measurement method and device

Abstract

The invention discloses a high-precision erythrocyte sedimentation rate (ESR) temperature compensation measurement method and device. The method comprises the steps: acquiring a to-be-corrected ESR value and an environment temperature value; performing equivalent preprocessing on the environment temperature value in the measurement process to obtain an equivalent environment temperature value; constructing a temperature compensation model of the ESR value based on the lagurre polynomial; obtaining fitting sample data, fitting the sample data through the ESR value temperature compensation model, and determining model parameters; testing the ESR value temperature compensation effect of the model, inputting uncorrected ESR value measurement data, and checking whether the compensated ESR valueis within the expected precision or not; if the error between the predicted value and the expected value is less than or equal to a preset target error, storing the model parameter data at the moment, generating an optimal ESR value temperature compensation model, and obtaining a ESR value temperature correction formula. According to the invention, the ESR value can be detected, the ESR measurement value is corrected through the correction formula obtained through the ESR value temperature compensation model, temperature compensation of the ESR measurement value can be rapidly and accuratelyachieved, and the ESR value detection precision is improved.

Description

technical field [0001] The invention belongs to the technical field of erythrocyte sedimentation value measurement, and in particular relates to a high-precision erythrocyte sedimentation rate temperature compensation measurement method and device. Background technique [0002] Erythrocyte sedimentation rate, referred to as erythrocyte sedimentation rate (ESR), the unit is mm / h, is an important detection index in the field of clinical medicine and medical research, and has a reference role in the diagnosis of a series of diseases. It is also one of the important diagnostic indicators for certain diseases. [0003] In the field of modern medicine, the erythrocyte sedimentation rate measured by the traditional manual Wei's method, Cooper's method, Wen's method, etc. and the erythrocyte sedimentation instrument are easily affected by the ambient temperature. High, can accelerate blood coagulation, on the contrary can delay blood coagulation, because the coagulation process is ...

AI Technical Summary

Problems solved by technology

When the temperature rises, or after the test tube is dried with hot air, the residual heat of the test tube has not been dissipated. When another blood sample is taken, due to the higher temperature, the enzyme activity is enhanced, which speeds up the coagulation reaction, which will have a certain impact on the ESR measurement.

However, in actual clinical testing and medical experiments, it is difficult to ensure that the measurement environment reaches the standard measurement temperature of 18 degrees Celsius by the Weiss method. Therefore, it is necessary to correct the temperature of the erythrocyte sedimentation rate

[0004] In the traditional erythrocyte sedimentation rate detection method, the table look-up method is often used for correction. This method is cumbersome to use. In addition, there is another method that uses a linear fitting algorithm to perform temperature compensation. Compared with the table look-up method, the accuracy of this method is limited. , and often only the ambient temperature value at the end of the ESR measurement is used as the measurement temperature for correction. In fact, the change of the measurement temperature during the measurement process cannot be taken into account, so that the correction value of the ESR value is not accurate.

Images