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Devices and assemblies for collection of biochemical samples

A sample collection and biochemical technology, applied in the preparation of test samples, measuring devices, instruments, etc., can solve the problems of separation sample band mixing and sample denaturation, increase separation efficiency and effect, capillary easy to block, etc., to reduce electrophoresis Time, good effect, effect of improving separation efficiency

Active Publication Date: 2021-12-31
WUXI NO 5 PEOPLES HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a device and components for biochemical sample collection, to solve the phenomenon of medium temperature rise caused by heat generation during electrophoresis separation of biochemical samples, resulting in mixing of separated sample bands and sample denaturation; solve the phenomenon that the capillary is easy to block; at the same time increase the separation Efficiency and effect, vacuum preservation of samples is beneficial to ensure the accuracy of detection, buffer solution can be recycled to reduce pollution, and all required types of separated samples can be separated and collected at one time

Method used

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  • Devices and assemblies for collection of biochemical samples
  • Devices and assemblies for collection of biochemical samples
  • Devices and assemblies for collection of biochemical samples

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Such as Figure 1-9 As shown, the device for collecting biochemical samples includes a collection and filtration mechanism 1 and a separation and purification mechanism 2. The collection and filtration mechanism 1 includes a cavity-11, the height of which is adjustable, and an opening and a built-in electrified electrode-14 The original sample collection bottle 13 is used to accommodate the biochemical samples to be processed, and is detachably connected to the opening side of the cavity one 11; the rotating mechanism one 12 includes a connecting shaft one connecting the notch one 121 and the screw mechanism 123 at both ends respectively 122, used to drive the original sample collection bottle 13 to move up and down along the cavity one 11, the cavity one 11 is divided into two regions by the filter diaphragm 124 connected in the middle of the connecting shaft one 122; There is a buffer solution 26 that can be transferred to the first cavity 11 and an electrode two 25 t...

Embodiment 2

[0057] When the device and assembly for biochemical sample collection of the present invention are actually used, the driving mechanism 3 is first fixed, and the cover 111a and cover 2 111b installed on the upper and lower holes of the side wall of the cavity 11 for sealing and antifouling are installed on the Pull out the leak-proof cover three 21a and cover four 21b on the upper and lower holes on the side wall of cavity two 21, connect the corresponding holes with a drainage tube, and swing the bottle body 271 of the separated sample collection bottle 27 into the turntable 223. The collected and filtered mechanism 1 and the separation and purification mechanism 2 after docking are adsorbed and suspended on the corresponding positions on the driving mechanism 3 . The original sample collection bottle 13 is screwed into the opening side of the cavity one 11 to form a closed space after collecting the samples. When the rotating mechanism one 12 rotates, under the guidance of th...

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Abstract

The invention discloses a device and an assembly for collecting biochemical samples, belonging to the technical field of biochemical equipment, comprising a collecting and filtering mechanism, a separation and purification mechanism and a driving mechanism; There is a through drainage tube horizontally connected between the mechanism and the separation and purification mechanism; the shunt mechanism of the separation and purification mechanism includes a shunt tube using the Venturi tube principle and a resistance circuit with different resistance values ​​connected in series; the driving mechanism can be connected to the first slot and the second slot. The connecting shaft 1 and the connecting shaft 2 are respectively driven to rotate, and the electrode 1 and the electrode 2 are connected for electrophoretic separation. It solves the phenomenon that the separation sample is mixed, the sample is denatured and the capillary is easy to block due to the heating of the medium temperature caused by the electrophoretic separation of the biochemical sample. The buffer solution is recycled to reduce pollution, the separation efficiency is high, the effect is good, and the vacuum preservation of the sample can ensure the accuracy of detection. It is able to separate and collect all desired types of separated samples at one time.

Description

technical field [0001] The invention belongs to the technical field of biochemical equipment, and in particular relates to devices and components for collecting biochemical samples. Background technique [0002] The collection of biochemical samples as a clinical activity to assist in the diagnosis and treatment of diseases is of great significance in clinical diagnostic applications. Clinical samples include blood, feces, urine, pleural and ascites, etc. The classification and counting of sample components, especially the rapid and accurate quantitative counting of some specific rare components, is very important for doctors to correctly diagnose the patient's condition and monitor the patient's recovery process. [0003] Patent US08062903B2 provides a method and apparatus for overcoming deleterious diffusion effects in a sample liquid stream by forming segmented liquids from the sample liquid stream in an immiscible liquid stream. Liquid is formed at the intersection of c...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N1/34G01N1/38G01N27/447
CPCG01N1/34G01N1/38G01N27/447
Inventor 刘君陈丽艳张时良赵新国
Owner WUXI NO 5 PEOPLES HOSPITAL
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