Traditional Chinese medicine composition for treating child precocious puberty and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and its preparation for treating precocious puberty in children, achieving the effects of convenient use, short course of treatment and low cost

Pending Publication Date: 2020-10-13
INCREASEPHARM TIANJIN INST CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, by consulting relevant research literature, it can be concluded that the above research is an exploratory study by Chinese medicine experts trying to find a safe, effective, and specially used for children's precocious puberty. At present, there is no effective Chinese patent medicine for the treatment of children's precocious puberty.

Method used

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  • Traditional Chinese medicine composition for treating child precocious puberty and preparation method thereof
  • Traditional Chinese medicine composition for treating child precocious puberty and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Take 24g of vinegar tortoiseshell and 30g of calcined oyster, add water to extract 2 times, the amount of water added each time is equivalent to 12 times the total weight of the two medicinal materials, each extraction time is 1 hour, filter, combine the filtrate, and set aside; 15g, Scrophulariaceae 15g, Anemarrhena 15g, Gentiana 10g, Saponaria thorn 15g, add water to extract 2 times after mixing, the amount of water added each time is equivalent to 12 times the total weight of the six herbs, each extraction time is 3 hours, filter , The filtrate is combined with the aforementioned extract, concentrated to a concentrated solution with a relative density of about 1.20 at 70°C, dried, and pulverized into fine powder. Take another 3 parts of excipient (the mixture of dextrin and soluble starch according to the weight ratio of 4:1), mix with fine powder, add 1 part of sucrose, add wetting agent, wet granulate, dry to make granules.

Embodiment 2

[0049] Take vinegar tortoise shell 18g, calcined oyster 24, add water to extract 2 times, the amount of water added each time is equivalent to 8 times the total weight of the two medicinal materials, each extraction time is 1 hour, filter, combine the filtrate, and set aside; 10g, Scrophulariaceae 10g, Anemarrhena 10g, Gentiana 8g, Saponaria thorn 12g, add water to extract 2 times after mixing, the amount of water added each time is equivalent to 8 times the total weight of the six herbs, each extraction time is 2 hours, filter , the filtrate is combined with the aforementioned extract, concentrated to a concentrated solution with a relative density of about 1.25 at 70°C, dried, pulverized into fine powder, added appropriate amount of auxiliary materials, mixed evenly, and further granulated to make capsules.

Embodiment 3

[0051] Take 12g of vinegar tortoise shell and 16g of calcined oyster, add water to extract 3 times, the amount of water added each time is equivalent to 8 times the total weight of the two medicinal materials, each extraction time is 3 hours, filter, combine the filtrate, and set aside; take gentian 6g, Extract 10g of saponins thorns with 60% ethanol under reflux for 3 times, each time the amount of ethanol is 8 times of the total amount of the two herbs, the extraction time is 2 hours, filter, combine the filtrates, recover the ethanol under reduced pressure, and set aside; the method of taking pinellia 6g , Poria 6g, Scrophulariaceae 6g, Anemarrhena 6g, add water to extract 3 times, the amount of water added each time is equivalent to 8 times of the total weight of the four medicinal materials, each extraction time is 2 hours, filter, the filtrate and the aforementioned two extracts Combined, concentrated to a concentrated solution with a relative density of 1.25 at 60°C, dri...

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Abstract

The invention belongs to the technical field of traditional Chinese medicine and particularly relates to a traditional Chinese medicine composition for treating child precocious puberty and a preparation method and a usage thereof. The traditional Chinese medicine composition is composed of the following components in parts by weight: 3-12 parts of rhizoma pinelliae, 5-15 parts of poria, 3-15 parts of radix scrophulariae, 6-15 parts of rhizoma anemarrhenae, 3-10 parts of radix gentianae, 6-24 parts of carapax et plastrum testudinis, 3-15 parts of spina gleditsiae and 6-30 parts of concha ostreae. The composition combines pharmacological research of modern Chinese medicine, takes a treatment rule of mainly clearing heat and dissipating phlegm with supplementation of softening and resolvinghard masses, addresses both symptoms and root causes, realizes internal and external regulation and is high in efficiency and free of obvious toxic and side reactions. Prescription application is flexible, and the cost is low. A particle drug made from the traditional Chinese medicine is not only significant in treatment effects, but is also short in treatment course, convenient to use and low inirritation. The preparation method is simple, the preparation cost is low and economic and clinical application values are high.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating precocious puberty in children, a preparation method and application thereof. Background technique [0002] Since the 1980s, the prevalence of precocious puberty among children in my country has been increasing year by year. In the past ten years, precocious puberty has gradually been paid attention to with the increase of incidence and the improvement of people's awareness. The "Guidelines for Diagnosis and Treatment of Precocious Puberty (Trial)" issued by the Ministry of Health in 2010 clearly defined that precocious puberty refers to the emergence of secondary sexual characteristics before the age of 9 for boys and 8 years for girls. That is, girls have breast enlargement before the age of 8, pubic hair and armpit hair growth before the age of 9, menstrual cramps and clitoris enlargement...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61K9/16A61P5/00A61P15/00A61K35/586A61K35/618
CPCA61K36/8888A61K36/076A61K36/8964A61K36/808A61K36/515A61K35/586A61K36/483A61K35/618A61K9/1652A61P5/00A61P15/00A61K2236/331A61K2236/39A61K2236/333A61K2236/51A61K2300/00
Inventor 陈永辉李艳英马莉李红刘伟李文慧杨秀伟
Owner INCREASEPHARM TIANJIN INST CO LTD
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