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A composition containing icodextrin and its application

An icodextrin content technology, applied in bandages, medical science, etc., to achieve the effect of promoting wound healing, convenient promotion and application, and good moisturizing performance

Active Publication Date: 2022-04-12
HUAREN PHARMACEUTICAL CO LTD +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are few medical dressings with the above functions on the market

Method used

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  • A composition containing icodextrin and its application
  • A composition containing icodextrin and its application
  • A composition containing icodextrin and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A medical applicator containing icodextrin, comprising the following composition by mass percentage: 8% icodextrin, 2% hyaluronic acid, 0.3% 1,2-hexanediol, 3% glycerin, 0.2 allantoin %, carbomer 0.4%, weigh the quality of each material according to the formula, dissolve icodextrin, hyaluronic acid, and carbomer in an appropriate amount of water for injection while stirring to form component A, and mix 1, 2-Hexanediol, glycerin, and allantoin are completely dissolved and mixed evenly under the condition of stirring to form the B component, and then slowly add the B component into the A component under the condition of stirring, and stir evenly. The sterilized non-woven patch is folded into a bag, the above-mentioned liquid is automatically filled and subpackaged, and then sealed, and the medical applicator containing icodextrin is obtained after passing the test.

Embodiment 2

[0021] A spray-type liquid dressing containing icodextrin, comprising the following composition in mass percentage: icodextrin 0.001%, hyaluronic acid 0.05%, modified chitosan 4%, sodium alginate 1%, according to the formula Weigh the mass of each substance, dissolve the modified chitosan in an appropriate amount of water for injection under stirring as component A, and dissolve sodium alginate in an appropriate amount of water for injection under stirring as group B Slowly add component A which has been stirred into component B and stir evenly, slowly add icodextrin and hyaluronic acid and stir evenly, then fill and sterilize, and after passing the test, you can get icodextrin Fine spray liquid dressing.

Embodiment 3

[0023] A gel-type medical dressing containing icodextrin, comprising the following composition by mass percentage: 5% icodextrin, 1% hyaluronic acid, 5% sodium alginate, 10% carboxymethyl chitosan, according to The formula weighs the quality of each substance, dissolves icodextrin, hyaluronic acid, and sodium alginate in an appropriate amount of water for injection under the condition of stirring to form A component, and dissolves carboxymethyl chitosan under the condition of stirring Dissolve in an appropriate amount of water for injection as component B, slowly add component A which has been stirred into component B and stir evenly, then fill and sterilize, and get the gel type containing icodextrin after passing the test Medical dressing.

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Abstract

The invention belongs to the field of medical dressings, and relates to a composition containing icodextrin for promoting wound healing and preventing scars, in particular to a formula containing the composition and an application method. An icodextrin-containing composition of the present invention is characterized in that: the composition contains icodextrin; and the mass content of the icodextrin is 0.001-8%. The composition containing icodextrin of the present invention has the effect of promoting wound healing and preventing scar. As a medical dressing, icodextrin has good biocompatibility, good permeability and hydration floating effect, so it has good anti-adhesion properties. At the same time, the raw material of icodextrin is starch, which is convenient and easy to obtain. It is more convenient to widely promote and apply. At the same time, hyaluronic acid has good moisturizing properties, and the combination of the two will play a synergistic role in promoting wound healing, anti-adhesion and moisturizing.

Description

technical field [0001] The invention belongs to the field of medical dressings, and relates to a composition containing icodextrin for promoting wound healing and preventing scars, in particular to a formula containing the composition and an application method. [0002] technical background [0003] Wounds can be defined as skin defects caused by mechanical, electrical, thermal, chemical and other factors or due to physiological abnormalities. Wound healing is the physiological response of body tissues to injury stimuli, and is generally divided into four stages: coagulation, inflammation, proliferation, and remodeling. heal. In a paper published by Winter R in 2003, it was found that through the study of pig body tissue, the wound healed faster in a closed moist environment than in a dry state, and proposed a theory of moist healing. Afterwards, many scientists repeated the research results of Winter R on the human body, and verified that moisturizing wounds heal faster, l...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L26/00
CPCA61L26/0023A61L26/0052A61L26/0014A61L26/008A61L26/0076A61L26/0066A61L2300/232A61L2300/412C08L5/02C08L5/08C08L5/04C08L33/02
Inventor 杨效东初晓君冯新光班文溥王盈盈谢苗苗
Owner HUAREN PHARMACEUTICAL CO LTD
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