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Measuring device and measuring method for high-flux monomolecular magnetic resonance

A measuring device and single-molecule technology, which can be applied in the direction of analysis using nuclear magnetic resonance, and can solve problems such as low measurement efficiency

Active Publication Date: 2020-10-27
UNIV OF SCI & TECH OF CHINA
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  • Claims
  • Application Information

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Problems solved by technology

However, the measurement efficiency of existing NV color center-based magnetic resonance spectroscopy measurement devices is low

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  • Measuring device and measuring method for high-flux monomolecular magnetic resonance
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  • Measuring device and measuring method for high-flux monomolecular magnetic resonance

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Embodiment Construction

[0053] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative work shall fall within the protection scope of the present invention.

[0054] In the following description, many specific details are explained in order to fully understand the present invention, but the present invention can also be implemented in other ways different from those described here, and those skilled in the art can do so without departing from the connotation of the present invention. Similar promotion, therefore, the present invention is not limited by the specific embodiments disclosed below. ...

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Abstract

The embodiment of the invention discloses a measuring device and a measuring method for high-flux single-molecule magnetic resonance. Laser emitted by a laser generating element in the measuring device is multi-point exciting light, and the phases of the multi-point exciting light are not completely the same, so that when the NV color centers in a diamond sample are excited, a plurality of NV color centers positioned on the light path of the multi-point exciting light can be excited at the same time, the plurality of NV color centers can be measured at one time, and the measurement efficiencyis improved. Besides, light spots formed by exciting light at all points of the device are small, so that when a plurality of NV color centers in the diamond sample are excited, the irradiation area of the exciting light at each point is small, a single NV color center can serve as a magnetic resonance sensing unit, the spatial resolution is high, and then measurement of signals of a single molecule is achieved.

Description

Technical field [0001] The invention relates to the technical field of magnetic resonance measurement, in particular to a high-flux single-molecule magnetic resonance measurement device and a measurement method. Background technique [0002] The nitrogen-vacancy center in diamond (nitrogen-vacancy center, referred to as NV color center) has been proved to have significant advantages in nanometer-scale magnetic field detection. For example, the electron spin freedom of NV color center can be microwaved. It is adjusted and initialized and read by optical means; the coherence time of NV color center at room temperature can be as long as milliseconds; NV color center is a kind of point defect inside diamond, and its size is only on the order of angstroms. The positioning accuracy under the system can reach the nanometer level. [0003] In 2015, Shi Kaifa, Zhang Qi, Wang Pengfei and others used NV color centers to measure the first magnetic resonance spectrum of a single protein molecu...

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Application Information

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IPC IPC(8): G01N24/08
CPCG01N24/08
Inventor 王鹏飞蔡明诚郭忠智石发展杜江峰
Owner UNIV OF SCI & TECH OF CHINA