Optimal chromosome karyotype map splicing method, optimal chromosome karyotype map splicing system and chromosome karyotype analysis method

A technology of chromosome karyotype and analysis method, which is applied in the field of chromosome karyotype map optimization splicing, can solve problems such as misdiagnosis and missed diagnosis, and achieve the effect of avoiding missed diagnosis and misdiagnosis and accurate karyotype analysis

Pending Publication Date: 2020-11-24
江苏医像信息技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional karyotype analysis doctors often only diagnose through a few karyotype maps, resulting in misdiagnosis and missed diagnosis.

Method used

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  • Optimal chromosome karyotype map splicing method, optimal chromosome karyotype map splicing system and chromosome karyotype analysis method
  • Optimal chromosome karyotype map splicing method, optimal chromosome karyotype map splicing system and chromosome karyotype analysis method
  • Optimal chromosome karyotype map splicing method, optimal chromosome karyotype map splicing system and chromosome karyotype analysis method

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Embodiment 1

[0035] figure 1 It is a flowchart of a method of a preferred stitching karyotype present invention.

[0036] like figure 1 Shown in Example 1 of the present embodiment provides a preferred karyotype FIG splicing method, comprising: filtering (preferably) chromosome; and splicing in accordance with the filtered chromosome karyotype FIG number of sheets, to achieve the image in the metaphase chromosome , preferably more than one splicing get clear and complete chromosome map; traditional karyotyping often only be diagnosed by a doctor a few karyotype map, leading to misdiagnosis and missed diagnosis of situation occurs, karyotype map by artificial intelligence algorithms judgment We need to identify as many karyotype diagram, (as much) karyotype analysis in order to more accurately map the chromosomal karyotype late according to the chromosome splicing after screening a number of sheets, to avoid misdiagnosis and missed diagnosis of the disease.

[0037] In the present embodiment, ...

Embodiment 2

[0042] Figure 4 It is a flowchart of a method of chromosome analysis according to the present invention.

[0043] like Figure 4 , In the embodiment 1 based on the embodiment, the second embodiment further provides a karyotyping method, comprising: acquiring image mitotic metaphase chromosome; obtaining a number of sheets in accordance with FIG karyotype mitotic metaphase chromosomes image (complete and clear FIG karyotyping); and karyotype karyotype analysis according to FIG.

[0044] In the present embodiment, the mitotic metaphase chromosomes according to the number of sheets acquired image karyotype FIG adapted to the above-described preferred karyotype FIG stitching method, a number of sheets acquired karyotype FIG.

[0045] In the present embodiment, the mitotic metaphase chromosomes image acquiring method comprising: preparing a cell chromosome specimen slides (e.g., blood samples, amniotic fluid, cord blood fluff and the like to prepare a cell chromosome specimen slides), ...

Embodiment 3

[0048] Figure 5 It is a block diagram of a preferred karyotype splicing system according to the present invention.

[0049] like Figure 5 , In the embodiment 1 based on the embodiment, the third embodiment also provides a karyotype FIG preferably splicing system, comprising: a filtering module, screening chromosome; and splicing module, the splicing in accordance with the filtered chromosome karyotype number of sheets picture.

[0050]In the present embodiment, the screening module screens the chromosome, and the splicing module is described in detail in the first embodiment according to the method of screening the chromosome stitching in Example 1, and will not be described in the present embodiment.

[0051] In summary, the present invention achieves a plurality of chromosome split phase images by screening chromosomes; and having a plurality of dyeing nuclear profiles according to the screening of chromosomes, it is preferable to obtain a plurality of clear and complete chromo...

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Abstract

The invention belongs to the technical field of chromosome analysis, and particularly relates to a chromosome karyotype map optimal splicing method, a chromosome karyotype map optimal splicing systemand a chromosome karyotype analysis method. The chromosome karyotype map optimal splicing method comprises the steps that chromosomes are screened; and according to the screened chromosomes, a plurality of chromosome karyotype graphs are spliced to obtain a plurality of clear and complete chromosome karyotype graphs through optimal splicing in the metaphase chromosome division phase images, so that later chromosome karyotype analysis is more accurate, and missed diagnosis and misdiagnosis of illness conditions are avoided.

Description

Technical field [0001] The present invention belongs to the technical field of chromosome analysis, particularly to a chromosome of a preferred stitching method, a system and method for karyotype analysis. Background technique [0002] Karyotype analysis is based on metaphase chromosomes as the research object, according to the length of the chromosome, centromere position, the ratio of the length of the arm, wherein the presence or absence with the peer, and by chromosome banding analysis, comparing, sorting and numbering , according to the variation of the structure and number of chromosomes for diagnosis. Karyotype analysis can cytogenetic classification, between species and provide an important basis for studies of variation in chromosome number and structure of kinship relations. For karyotype analysis requires complete and clear genome and a large number of full karyotype map. The traditional karyotyping often only be diagnosed by a doctor a few karyotype map, leading to mi...

Claims

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Application Information

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IPC IPC(8): G06T3/40G16B20/00
CPCG06T3/4038G16B20/00
Inventor 包勇文耀锋
Owner 江苏医像信息技术有限公司
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