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Tibetan medicine manuoxitang constipation-treating granule and preparation method thereof

A granule and constipation technology, applied in the field of Tibetan medicine, can solve the problems of poor bioavailability, large drug dose, and backward dosage form

Inactive Publication Date: 2020-11-27
青海省藏医药研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The formula of Manuo Decoction Constipation Tong is used in traditional decoctions, powders, pills and capsules mainly made of raw medicine powder in the outpatient clinics of famous old Tibetan doctors in Tibetan areas and major hospitals. There are relatively large drug doses and outdated dosage forms. , inconvenient taking, slow absorption, slow action, poor bioavailability and other deficiencies have affected the marketing and application of the above Tibetan medicine preparations

Method used

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  • Tibetan medicine manuoxitang constipation-treating granule and preparation method thereof
  • Tibetan medicine manuoxitang constipation-treating granule and preparation method thereof
  • Tibetan medicine manuoxitang constipation-treating granule and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0035] The formula of embodiment 1 Manuo system soup constipation-relieving composition

[0036] There are 12 parts of Tibetan woody fragrance, 25 parts of raspberry, 12 parts of broad tendon rattan, 9 parts of myrobalan, 9 parts of rhubarb and 9 parts of alkali flower.

[0037] Preparation Process:

[0038] 1. Raw material pretreatment:

[0039] (1) Zangmuxiang removes impurities, rinses it with running water, and cuts it off; put the alkali flower in water, pour off the upper layer mixed with impurities, and take out the lower layer of precipitated drug alkali flower. The treated Tibetan woody fragrance and alkali flower are respectively dried in the drying room at a temperature of 70°C to 80°C. After drying, they are placed in the irradiation room and sterilized by ultraviolet light. The thickness of the laying is ≤5cm, and every 30 Flip once every minute, and the irradiation time is 300 minutes. The Tibetan woody fragrance and the alkali flower are respectively pulveriz...

Embodiment 2-4

[0051] The formula of Manuo Decoction Constipation Constipation Composition is shown in the following table 1

[0052] The formula (parts by weight) of the constipation-relieving composition of table 1 embodiment 2-4

[0053] herbs Example 2 Example 3 Example 4 Tibetan woody fragrance 10 15 12 raspberry 30 20 25 broad vine 15 12 15 Myrobalan 8 9 10 rhubarb 10 8 9 Alkaline flower 8 10 9

[0054] Preparation process: refer to the method of Example 1.

Embodiment 5

[0055] Embodiment 5 preparation process condition selection

[0056] Because part of the ingredients of this granule is boiled and extracted. In order to maintain the complete extraction of the original ingredients of the medicinal materials, the water boiling extraction conditions are now tested and confirmed. Determine the extraction process that is suitable for actual production, and is more suitable for large-scale batch production of solid instant granules. 2560g raw material, according to the decoction extraction and concentration method of embodiment 1, because what different tests obtain is extractum, there are differences in the degree of concentration, and the data conditions recorded are different. Density d=1.30 is the calculation standard. The influencing factors of the test are: the amount of water for the second boiling, the time, and the degree of brokenness of the medicinal materials. The test results are shown in Table 2.

[0057] Table 2 Analysis table o...

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Abstract

The present invention discloses a Tibetan medicine manuoxitang constipation-treating granule and a preparation method thereof. The granule is made of the following medicinal materials in parts by weight: 10-15 parts of Tibet inula root, 20-30 parts of rubus corchorifolius, 10-15 parts of caulis tinosporae sinensis, 8-10 parts of fructus chebulae, 8-10 parts of Chinese rhubarb and 8-10 parts of tronae. The granule solves problems that traditional manuoxitang constipation-treating soup is inconvenient to use, quality is difficult to control and commercialized production is difficult, and also has an obvious curative effect on treating constipation.

Description

technical field [0001] The invention belongs to the technical field of Tibetan medicine, and in particular relates to a Tibetan medicine Manuoxitang Bianbitong granule and a preparation method thereof. Background technique [0002] Tibetan medicine prescriptions are a summary of the experience of thousands of years of medical development. It is an important part of the treasure house of Chinese medicine. With its unique medicinal resources, complex and diverse processing techniques, and unique curative effects, it has broad research and development value and industrial development prospects. [0003] Manuoxi Decoction in Tibetan medicine prescriptions is a classic prescription of Tibetan medicine. It was first published in the "Si Bu Yi Dian" in the 8th century AD, and has a clinical application history of more than 1,000 years. The basic formula of Manuo soup is composed of three medicinal materials: Tibetan woody incense, raspberry and broad tendon rattan. It is used to ...

Claims

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Application Information

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IPC IPC(8): A61K36/73A61P1/10A61K9/16A61K33/00
CPCA61K36/28A61K36/73A61K36/59A61K36/185A61K36/708A61K33/00A61P1/10A61K2236/331A61K2236/39A61K9/1682A61K2236/51A61K2300/00Y02A50/30
Inventor 多杰东知多杰赛桑杰佳哇尼玛才让
Owner 青海省藏医药研究院
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