9 results about "Rubus corchorifolius" patented technology

The present application provides a method for extracting complex organic acid from the waste liquid of the extract of Rubus corchorifolius L.f. The waste liquid of the column chromatography effluent of the Rubus corchorifolius L.f. extract is taken, the specific gravity of the secondary waste liquid is adjusted to obtain the column loading liquid, the column loading liquid is passed through a resin column A, water washing is performed, the column effluent and the water washing liquid are collected to obtain a combined liquid 1, the combined liquid 1 is passed through a resin column B, water washing is performed, reagent C is used for elution, and the eluate is collected. The combined liquid 2 is obtained by passing through a resin column D and collecting the effluent and the water washing liquid, vacuum concentration is performed, crystallization is performed, and filtration is performed to obtain quinic acid.

The invention discloses application of geum aleppicum total triterpenes in treatment of hypertension and a preparation method of the geum aleppicum total triterpenes, the geum aleppicum total triterpenes are obtained by step-by-step extraction and purification of geum aleppicum, and the geum aleppicum total triterpenes comprise bitter raspberry sweet F1, 2-hydroxyl oleanolic acid, 2-hydroxyl ursolic acid, 20beta, 20beta, 20beta, 20beta, 20beta, 20beta, 20beta, 20beta, 20beta The traditional Chinese medicine composition is prepared from the following raw materials in percentage by weight: 28-epoxy-28-hydroxytaxasan-3 beta-ol (taraxane triterpenes), ursolic acid, maslinic acid, rosa multiflora acid and tormentic acid. According to the present invention, the geum aleppicum total triterpenes are extracted and purified from the geum aleppicum step by step, and the geum aleppicum total triterpenes can significantly increase the total cross-sectional area of the vascular bed of the ischemic tissue or organ, such that the low blood pressure can meet the blood perfusion for maintaining the life activity so as to achieve the blood pressure lowering purpose; the compound can be widely applied to the field of hypertension prevention and treatment medicines.

The invention discloses a ferulic acid derivative and a preparation method and application thereof.The ferulic acid derivative is a compound shown in the formula (I) or pharmaceutically acceptable salt of the compound, and the compound is a natural compound extracted from rubus corchorifolius stems, has anti-inflammatory activity and anti-tumor activity and has the potential of being developed into anti-inflammatory or anti-tumor drugs. Or as a lead compound.

The present application relates to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for controlling obesity. The traditional Chinese medicine composition comprises Pueraria pedunculata, Lantana camara, Curcuma longa, Curcuma wenyujin, Curcuma roxburghii, Angelica sinensis, Boswellia carterii, Commiphora myrrha, Semen Persicae, Radix Polygoni multiflori and Rubus corchorifolius. The traditional Chinese medicine composition can effectively regulate blood fat by external use, thereby achieving the effects of improving obesity-related metabolic disorders and controlling obesity. In addition, the traditional Chinese medicine composition has no skin irritation when used externally, and has no acute toxicity at a dosage much higher than a clinical dosage, and is safe and reliable to use, and has a wide application prospect in controlling obesity.

The application provides a preparation method of Rubus corchorifolius extract and application thereof, and belongs to the technical field of traditional Chinese medicine pharmacy. The preparation method is simple in steps and does not produce toxic and harmful substances. The Rubus corchorifolius extract prepared by the application can inhibit skin tissue structure damage, collagen fiber reduction, elastic fiber damage and reduction of mast cell infiltration, and is effectively used for skin photodamage. Compared with a UVB model group, after intervention of a TFDI low-dose group and a TFDI high-dose group, skin photodamage scores are reduced by 1.7306 and 2.3184 respectively; epidermal thickness is reduced by 0.8572 microns and 1.3627 microns respectively; dermal thickness is reduced by 0.4767 microns and 0.8370 microns respectively; and collagen content is increased by 64.95% and 126.65% respectively. The Rubus corchorifolius cream prepared by the application can treat and / or prevent skin photodamage, and has no obvious toxicity in an in-vitro experiment, and exhibits good safety.

The application provides a traditional Chinese medicine composition and application thereof in preparation of anti-fatigue health care wine, and relates to the technical fields of traditional Chinese medicine pharmacy and health care. The traditional Chinese medicine composition is prepared from medicinal and edible traditional Chinese medicinal materials, and is composed of Cistanche, Acanthopanax, Radix Asparagi, Phyllanthus emblica, Typha angustifolia, Terminalia, Chrysanthemum, Rubus corchorifolius, Canavalia, and Citrus medica, and has the effects of tonifying kidney and spleen, benefiting qi and nourishing yin, and clearing and tonifying. The traditional Chinese medicine composition and the health care wine prepared from the traditional Chinese medicine composition have excellent anti-fatigue effects, can significantly prolong the exhaustive swimming time of mice under load, significantly reduce the urea nitrogen content in plasma of mice after exercise, significantly increase the liver glycogen content of mice, significantly increase the blood lactic acid clearance rate of mice after exercise, and have a significant effect of relieving physical fatigue. The traditional Chinese medicine composition is expected to be developed into an anti-fatigue drug or health care product.

The invention provides a traditional Chinese medicine composition for inhibiting osteosarcoma progress by activating macrophages, and relates to the technical field of traditional Chinese medicine preparations and immunoregulation. The traditional Chinese medicine composition for inhibiting osteosarcoma progress by activating macrophages is prepared from the following traditional Chinese medicinal materials in parts by weight: 20 to 40 parts of radix astragali seu hedysari, 5 to 15 parts of bulbus fritillariae thunbergii, 20 to 40 parts of semen coicis, 20 to 40 parts of herba hedyotidis diffusae, 4 to 8 parts of radix platycodonis, 10 to 20 parts of herba salviae chinensis, 10 to 20 parts of radix cudramiae, 10 to 20 parts of pumice and auxiliary medicinal materials. According to the invention, macrophages are induced to be polarized to M1 type, so that the phagocytic ability and cytokine release of the macrophages are enhanced, and tumor cells are killed and inhibited. In-vitro and in-vivo experiments show that the traditional Chinese medicine composition can significantly enhance the anti-tumor activity of macrophages and inhibit proliferation, migration and metastasis of tumor cells, so that a safe and effective traditional Chinese medicine scheme is provided for tumor immunotherapy.

This invention relates to the field of traditional Chinese medicine quality testing technology, specifically to an HPLC fingerprint spectrum of *Caulis Amaranthus urinaria* (also known as *Caulis Amaranthus urinaria*), its construction method, and its application. The construction method includes the following steps: preparation of a test solution, preparation of a mixed reference solution, fingerprint spectrum construction, multi-component quantitative analysis, and chemical pattern recognition. This invention combines HPLC fingerprinting, multi-component quantitative analysis, and chemical pattern recognition technologies, enabling efficient and accurate characterization of the overall quality of *Caulis Amaranthus urinaria* and precise evaluation of its differences. This provides a basis for the formulation of quality standards, quality control, selection of superior production areas, and selection of clinical medications for *Caulis Amaranthus urinaria*.

The application belongs to the technical field of traditional Chinese medicine, and particularly relates to a preparation method and application of a Gastrodia elata Yin-boosting oral preparation. The oral preparation comprises the following raw materials in parts by weight: Gastrodia elata 20-25 parts, Rehmannia glutinosa 15-20 parts, Cornus officinalis 14-17 parts, Fructus Lycii 17-21 parts, Rubus corchorifolius 15-20 parts, Anoectochilus roxburghii 10-15 parts, Ophiopogon japonicus 10-20 parts, Polygonatum odoratum 10-14 parts, Panax ginseng 5-10 parts, Atractylodes macrocephala 7-12 parts, Poria cocos 5-10 parts, Ziziphus jujuba var. spinosa 10-15 parts, Schisandra chinensis 5-10 parts, Angelica dahurica 5-8 parts, Angelica sinensis 1-5 parts, and Glycyrrhiza uralensis 3-8 parts. Animal experiments prove that the oral preparation can prolong the exhaustive swimming time of mice, reduce the content of blood lactic acid and serum urea of mice after swimming, increase the storage of liver glycogen, and has a significant anti-fatigue effect.