Stem cell preparation for treating diabetic foot and preparation method thereof

A technology of stem cell preparation and diabetic foot, which is applied in the field of biological preparations, can solve the problems of high cure rate, limited drug treatment effect, susceptibility to infection, etc.

Inactive Publication Date: 2021-02-12
广州广迈生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When diabetic patients have foot damage, it is difficult to heal. Because the wound is on the foot, it is easy to be infected. It takes a long time for the wound to heal, and the area spreads quickly, which doubles the pain of the patient.
[0003] At present, diabetic foot is alleviated by d...

Method used

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specific Embodiment approach

[0018]A stem cell preparation for treating diabetic foot, said preparation comprising: umbilical cord mesenchymal stem cells, islet cells and glycine, wherein the density of said umbilical cord mesenchymal stem cells is 104~106Pcs / ml, this embodiment is preferably 105Pcs / ml; the concentration of the islet cells is 106~108Pcs / ml, this embodiment is preferably 107Pcs / ml; the concentration of glycine is 1-5 mg / ml, and this embodiment is preferably 3 mg / ml; in the composition of the preparation, the ratio of umbilical cord mesenchymal stem cells, islet cells, and glycine is: (104~106Pcs): (106~108A): (100~500mg); the preparation also includes fibroblasts at a concentration of 1~5×106Pcs / ml, this embodiment is preferably 3×106Pcs / ml.

[0019]Further, in the composition of the preparation, the ratio of umbilical cord mesenchymal stem cells to fibroblasts is 0.1-1:5.

[0020]Use of a stem cell preparation for treating diabetic foot in preparing medicine for treating diabetic foot.

[0021]A prepara...

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PUM

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Abstract

The invention relates to a biological agent, in particular to a stem cell preparation for treating diabetic foot and a preparation method of the stem cell preparation, the stem cell preparation comprises umbilical cord mesenchymal stem cells, islet cells and glycine, the density of the umbilical cord mesenchymal stem cells is 104-106/ml, the concentration of the islet cells is 106-108/ml, and theconcentration of the glycine is 1-5mg/ml; the stem cell preparation is used for treating diabetic feet, totipotency of stem cells can be differentiated into different cells, completeness of foot injury can be supplemented through the stem cells, and meanwhile, umbilical cord mesenchymal stem cells, islet cells, glycine and fibroblasts react together and have a synergistic effect, so that functionsof the stem cells are enhanced, and the effect of treating diabetic feet is achieved. And preparing the stem cell preparation for effectively treating the diabetic foot.

Description

Technical field[0001]The invention relates to a biological preparation, in particular to a stem cell preparation for treating diabetic foot and a preparation method thereof.Background technique[0002]Diabetic foot refers to the condition of diabetic neuropathy. The protective function of the lower limbs of diabetic feet is reduced due to neuropathy. The arterial insufficiency caused by macrovascular and microvascular disease causes ulcers and gangrene. It includes peripheral nerve sensory disorders and plants. Nerve damage, lower extremity vascular disease, arteriosclerosis caused by peripheral arteriolar occlusion, or skin microvascular disease and bacterial infection caused by foot pain, foot ulcers and foot gangrene and other diseases. When the feet of diabetic patients suffer from foot damage, it is more difficult to heal. Because the wound is on the foot, it is easy to be infected. It takes a long time for the wound to heal, and the range spreads quickly, which makes the patient...

Claims

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Application Information

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IPC IPC(8): A61K35/39A61P17/02A61P3/10A61K35/28A61K35/35A61K31/198
CPCA61K31/198A61K35/28A61K35/35A61K35/39A61P3/10A61P17/02A61K2300/00
Inventor 杨丰华
Owner 广州广迈生物科技有限公司
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