Non-irritant acne-removing makeup base and preparation method thereof

A technology of isolation cream and silk protein, which is applied in the directions of botanical equipment and methods, biochemical equipment and methods, chemical instruments and methods, etc., can solve the problem of clogged pores, the inability to fundamentally improve the skin, care for acne marks, and worsen acne Skin and other problems, to achieve the effect of protecting the skin, protecting the skin from damage, and inhibiting the growth

Inactive Publication Date: 2021-03-09
王森阳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although the barrier cream has the effect of covering acne marks, it cannot fundamentally improve the skin and care for acne marks; the added titanium dioxide, which has a good anti-radiation effect, can easily clog pores and worsen acne-prone skin if it is not cleaned properly

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0035] A preparation method of non-irritating acne-removing segregation cream, comprising the following specific steps:

[0036] Step 1: Add tangerine peel, Chinese yam, Bupleurum, Citrus aurantii, Curcuma, Bergamot, Paeoniae Alba, Prunella vulgaris, and green tea into the nanoemulsion gel, and stir at 90°C for 3 hours at 120-200rpm to obtain phase A;

[0037] Step 2: Slowly add the pseudophysalis extract and fibroin titanium dioxide nanoparticle microcapsules to the phase A obtained in step 1, and stir at 150-200 rpm at 30°C for 2 hours to obtain a non-irritating acne-removing isolation cream.

[0038] According to the above technical scheme, the nanoemulsion gel is obtained by adding a 5-100nm pseudophysalis seed gum matrix based on the nanoemulsion; RH-40 is a surfactant, and tert-butanol is a cosurfactant.

[0039] According to the above technical scheme, the silk protein titanium dioxide nanoparticle microcapsules are prepared using the self-assembly technology of the spi...

Embodiment 1

[0050] A non-irritating anti-acne isolation cream, including 12 parts of pseudophysalis extract, 10 parts of nanoemulsion gel, 4 parts of silk protein titanium dioxide nanoparticle microcapsules, 0.5 part of tangerine peel, 0.2 part of Chinese yam, 0.8 part of white peony root, green tea 0.6 parts, 3 parts of water.

[0051] A preparation method of non-irritating acne-removing segregation cream, comprising the following specific steps:

[0052] Step 1: Add tangerine peel, Chinese yam, Bupleurum, Citrus aurantium, Curcuma, Bergamot, Paeoniae Alba, Prunella vulgaris, and green tea to the nanoemulsion gel, stir at 90°C and 150rpm for 3 hours, and obtain phase A;

[0053] Step 2: Slowly add the pseudophysalis extract and fibroin titanium dioxide nanoparticle microcapsules to the phase A obtained in step 1, and stir at 180 rpm at 30°C for 2 hours to obtain a non-irritating acne-removing isolation cream.

[0054] According to the above technical scheme, the nanoemulsion gel is obta...

Embodiment 2

[0065] A non-irritating anti-acne isolation cream, including 15 parts of pseudophysalis extract, 12 parts of nanoemulsion gel, 3 parts of silk protein titanium dioxide nanoparticle microcapsules, 0.5 part of tangerine peel, 0.2 part of Chinese yam, 0.8 part of white peony root, green tea 0.6 parts, 3 parts of water.

[0066] A preparation method of non-irritating acne-removing segregation cream, comprising the following specific steps:

[0067] Step 1: Add tangerine peel, Chinese yam, Bupleurum, Citrus aurantium, Curcuma, Bergamot, Paeoniae Alba, Prunella vulgaris, and green tea to the nanoemulsion gel, stir at 90°C and 150rpm for 3 hours, and obtain phase A;

[0068] Step 2: Slowly add the pseudophysalis extract and fibroin titanium dioxide nanoparticle microcapsules to the phase A obtained in step 1, and stir at 200 rpm at 30°C for 2 hours to obtain a non-irritating acne-removing isolation cream.

[0069] According to the above technical scheme, the nanoemulsion gel is obta...

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Abstract

The invention discloses non-irritant acne-removing makeup base and a preparation method thereof. The makeup base is prepared from nicandra physaloides extract, nanoemulsion gel, fibroin titanium dioxide nanoparticle microcapsules, pericarpium citri reticulatae, rhizoma dioscoreae, radix paeoniae alba, green tea and water. The R9-EGF recombinant gene is inserted into agrobacterium rhizogenes, the agrobacterium rhizogenes are used for infecting the physalis alkekengi explant, a large amount of R9-EGF composite protein is expressed, and the skin permeability of macromolecular EGF is solved. The nano-emulsion gel is prepared by combining nano-emulsion and nicandra physaloides seed gum, has a polymer network structure and can contain a large amount of water and liquid medicine; and by increasing the content of a thickening agent in the nano-emulsion gel and adjusting the diameter of an internal screen, the nano-emulsion gel becomes an excellent drug carrier. Titanium dioxide nanoparticles are wrapped with fibroin to be prepared into microcapsules, so that the titanium dioxide nanoparticles have good water solubility, the stability of an aqueous solution can be maintained, irritation andallergy to skin are avoided, and the skin is protected against ultraviolet radiation.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a non-irritating acne-removing isolation cream and a preparation method thereof. Background technique [0002] Epidermal growth factor (EGF) is a polymorphic single-chain small molecule containing 53 amino acids, with a molecular weight of about 6.2KD. EGF has a strong promoting effect on various cell proliferation and epidermal tissue growth, and has been used in the treatment of various wounds, ulcers and corneal injuries in medicine. In addition, EGF can also promote the metabolism of normal epidermal cells, and as a cosmetic additive, it can be added to beauty and skin care products to achieve the effects of whitening, anti-wrinkle, and anti-aging. Therefore, no matter it is as a medical drug or a cosmetic additive, EGF has huge potential application value and Broad market prospects. However, studies have shown that the transdermal rate of EGF is very low, and the cumulat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61K8/11A61K8/29A61K8/64A61K8/9789A61K8/04A61K36/8945A61Q19/08A61Q19/00A61Q17/00A61P17/10C12N15/82C12N15/62A01H5/06A01H6/82
CPCA61K8/9789A61K8/64A61K8/29A61K8/11A61K8/042A61K8/9794A61Q19/00A61Q17/005A61Q19/08A61P17/10A61K36/81A61K36/752A61K36/8945A61K36/82A61K36/71A61K36/65C12N15/8213C12N15/8257C07K14/485A61K2800/86C07K2319/10A61K2300/00
Inventor 王森阳
Owner 王森阳
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