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Liquid chromatography thermal system with thermal status detection

A technology of liquid chromatography and liquid chromatography column, which is applied in the thermal state of the hot chamber and the field of liquid chromatography thermal system, which can solve problems such as temperature rise, unexpected engine failure, and engine performance degradation

Pending Publication Date: 2021-03-09
WATERS TECH CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

When ice accumulates, the performance of the engine that controls the temperature decreases and the temperature inside the hot chamber will rise undesirably
In addition, sometimes the engines that control the thermal chambers of these systems fail unexpectedly

Method used

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  • Liquid chromatography thermal system with thermal status detection
  • Liquid chromatography thermal system with thermal status detection
  • Liquid chromatography thermal system with thermal status detection

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Embodiment Construction

[0027] Reference in this specification to "one embodiment" or "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment of the present teachings. References to a particular embodiment within this specification are not necessarily all referring to the same embodiment.

[0028] The present teachings will now be described in more detail with reference to exemplary embodiments of the present teachings as illustrated in the accompanying drawings. While the present teachings are described in connection with various embodiments and examples, the present teachings are not intended to be limited to such embodiments. In contrast, the present teachings encompass various alternatives, modifications, and equivalents, as will be understood by those skilled in the art. Those of ordinary skill having access to the teachings herein will recognize additional implementations, modifications, an...

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Abstract

A device and a method for determining a status of a thermal chamber in a liquid chromatography system. The method (200) includes a step (210) of monitoring the temperature of a heat sink, a thermal chamber and / or an ambient temperature outside the thermal chamber. A step (212) sends these temperature measurements made by the sensors (110,111,112) to a computer system (120). The method (200) includes another step (220) of monitoring the power use of a heater / cooler engine, and sending (222) power information to the computer system (120). The method steps (210) and (212) may be occurring simultaneous to the method steps (220), (222) in one embodiment. The method (200) further includes a step (230) of receiving the temperature measurements and the power information generated or taken by the sensors from the steps (210), (212), (220), and (222), by the computer system. A next step (232) analyzes the temperature measurements, information, data or the like that is received and determines (234) a status, such as whether ice has formed on a heat sink of the system.

Description

[0001] related application [0002] This application is claiming priority to U.S. Provisional Patent Application No. 62 / 700995, filed July 20, 2018, entitled "Liquid Chromatography Thermal System With Ice Detection and Prevention" , which is incorporated herein by reference. technical field [0003] The present invention generally relates to liquid chromatography systems. More particularly, the present invention relates to liquid chromatography thermal systems, or liquid chromatography sample managers and / or sample organizers, and related systems and methods for detecting the thermal state of a thermal chamber therein. Background technique [0004] Chromatography is a group of techniques for separating a mixture into its components. For example, in a liquid chromatography system, a pump draws in a mixture of liquid solvents and delivers it to a sample manager, where the injected sample awaits its arrival. The mobile phase, consisting of the sample dissolved in a solvent m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/30
CPCG01N30/30G01N2030/3007G01N2035/00435G01N30/88G01N2030/027G01N25/04
Inventor D·A·辛普森C·查普特M·M·索雷斯
Owner WATERS TECH CORP