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Dazhuanzhong decoction semisolid preparation and preparation method thereof

A Dajianzhong decoction and semi-solid technology, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of easy deterioration, large dose of Chinese medicine decoction, instability, etc., and achieve easy preservation. , The effect of increasing food intake and body weight, and taking convenient

Inactive Publication Date: 2021-03-30
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The decoction of traditional Chinese medicine has a large dose, is easy to deteriorate, and is unstable. The decoction is one of the traditional dosage forms of traditional Chinese medicine. Its advantage is that it is concentrated, small in size, and easy to take. In addition, the ointment contains refined honey or sugar, which has the effect of nourishing and strengthening the body. Therefore, traditional Chinese medicine is mostly used to treat chronic diseases, and it is a better dosage form among nourishing patent medicines. At present, there is no report on the semi-solid preparation of Dajianzhong Decoction

Method used

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  • Dazhuanzhong decoction semisolid preparation and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0026] Embodiment 1, the preparation of Dajianzhongtang semi-solid preparation of the present invention

[0027] Recipe: 6g pepper, 12g dried ginger, 6g ginseng, 30g maltose, 1g mixed gum, 1g flavoring agent.

[0028] Preparation:

[0029] (1) Weigh the raw and auxiliary materials according to the formula;

[0030] (2) Take Zanthoxylum bungeanum, dried ginger, and ginseng, mix well, add 10 times the amount (v / w; ml / g) of water to decoct for 30 minutes, filter, add maltose and concentrate until the relative density is 1.30-1.40, and then the decoction is obtained;

[0031] (3) Take the mixed gel, add decoction and flavoring agent in sequence under stirring, concentrate to a fixed volume, pour the gel into the mold while it is hot, let it stand and cool until the gel is formed, and sterilize to get Dajianzhong Decoction jelly.

Embodiment 2

[0032] Embodiment 2, the preparation of Dajianzhongtang semi-solid preparation of the present invention

[0033] Recipe: 4.2g pepper, 8.4g dried ginger, 4.2g ginseng, 30g maltose, 0.7g mixed gum, 1g flavoring agent.

[0034] Preparation:

[0035] (1) Weigh the raw and auxiliary materials according to the formula;

[0036] (2) Take Zanthoxylum bungeanum, dried ginger, and ginseng, mix well, add 10 times the amount (v / w; ml / g) of water to decoct for 30 minutes, filter, add maltose and concentrate until the relative density is 1.30-1.40, and then the decoction is obtained;

[0037] (3) Take the mixed gel, add decoction and flavoring agent in sequence under stirring, concentrate to a fixed volume, pour the gel into the mold while it is hot, let it stand and cool until the gel is formed, and sterilize to get Dajianzhong Decoction jelly.

Embodiment 3

[0038] Embodiment 3, the preparation of Dajianzhongtang semi-solid preparation of the present invention

[0039] Recipe: pepper 7.8g, dried ginger 15.6g, ginseng 7.8g, maltose 30g, mixed gum 1.3g, flavoring agent 1g.

[0040] Preparation:

[0041] (1) Weigh the raw and auxiliary materials according to the formula;

[0042] (2) Take Zanthoxylum bungeanum, dried ginger, and ginseng, mix well, add 10 times the amount (v / w; ml / g) of water to decoct for 30 minutes, filter, add maltose and concentrate until the relative density is 1.30-1.40, and then the decoction is obtained;

[0043] (3) Take the mixed gel, add decoction and flavoring agent in sequence under stirring, concentrate to a fixed volume, pour the gel into the mold while it is hot, let it stand and cool until the gel is formed, and sterilize to get Dajianzhong Decoction jelly.

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Abstract

The invention discloses a Dazhuanzhong decoction semisolid preparation and a preparation method thereof. The Dazhuanzhong decoction semisolid preparation is prepared from the following raw material medicines in parts by weight: 4.2-7.8 parts of Chinese prickly ash, 8.4-15.6 parts of dried ginger, 4.2-7.8 parts of ginseng and 21-39 parts of maltose. The Dajianzhong decoction semisolid preparation has the effects of warming the middle warmer, tonifying deficiency, calming the adverse-rising energy and relieving pain, and also has the treatment effects of nourishing and relaxing; the Dajianzhongdecoction decoction semisolid preparation can improve the general state of rats with spleen-yang deficiency, relieve symptoms such as emaciation, fatigue and weakness, cold limbs and diarrhea, increase food intake and weight, increase anus temperature, remarkably improve swimming endurance (p is less than 0.01), remarkably increase organ indexes (p is less than 0.01) and effectively treat spleen-yang deficiency. Besides, the Dajianzhong decoction semi-solid preparation has excellent color, impurities, flavor and tissue form, is small in size, good in stability, easy to store, good in taste andconvenient to take, and has good clinical popularization and application value.

Description

technical field [0001] The invention specifically relates to a semi-solid preparation of Dajianzhong decoction and a preparation method thereof. Background technique [0002] Dajianzhong Decoction comes from "Synopsis of the Golden Chamber". It is composed of ginseng (codonopsis pilosula is often used in prescriptions), dried ginger, Sichuan pepper, and maltose. It is mainly used to treat severe epigastric pain syndrome caused by weakness of Zhongyang and excess of Yin-cold in the interior. Now it is mostly used to improve postoperative intestinal obstruction. [0003] The decoction of traditional Chinese medicine has a large dosage, is easy to deteriorate, and is unstable. The decoction is one of the traditional dosage forms of traditional Chinese medicine. It has the advantage of being concentrated, small in size, and easy to take. In addition, the ointment contains refined honey or sugar, which has the effect of nourishing and strengthening the body. Therefore, tradition...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P1/14A23L33/105A23L21/10A61K31/7016
CPCA23V2002/00A61K9/0056A61K31/7016A61K36/258A61K36/758A61K36/9068A61K2236/331A61K2236/51A23L21/10A23L33/105A61P1/14A61K2300/00A23V2250/21A23V2250/2124
Inventor 吴纯洁彭伟张萌萌魏大能黄永亮赵容王丹叶洵
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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