Whole liver bioartificial liver support system dedicated tubing

A bioartificial and pipeline technology, applied in the field of medical devices, can solve the problems of inapplicable whole-liver bioartificial liver, inconvenient assembly and disassembly of pipelines, poor liver perfusion, etc., to reduce economic burden, easy to disassemble, The effect of easy connection

Active Publication Date: 2021-09-17
GUANGDONG UNISUN BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current whole-liver artificial liver system has problems such as system complexity and poor liver perfusion, which limit its further popularization and application.
[0003] In addition, the current whole-liver bioartificial liver system does not have matching pipelines. In order to realize the mutual cooperation of different treatment modes, it is often necessary to disassemble and reconnect the pipelines according to actual needs, and the current pipelines are not suitable. Whole-liver bioartificial liver, resulting in inconvenient assembly and disassembly of pipeline connections and complex structure

Method used

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  • Whole liver bioartificial liver support system dedicated tubing
  • Whole liver bioartificial liver support system dedicated tubing
  • Whole liver bioartificial liver support system dedicated tubing

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Embodiment Construction

[0040] Embodiments of the present application are described in detail below, examples of which are shown in the drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the figures are exemplary only for explaining the present application, and are not construed as limiting the present application.

[0041] See Figure 1 to Figure 8 , in order to adapt to the use of the whole-hepatic bioartificial liver system, this application provides a special pipeline for the whole-hepatic bioartificial liver system. Circulating pipelines: arterial pipeline 11, venous pipeline 12, plasma separation pipeline 13, blood storage tank drainage tube 21, pre-hepatic pipeline 22, post-hepatic pipeline 23, circulation pipeline 31 and plasma return tube Road 32. Wherein, the plasma separation cycle includes an arterial line 11, a venous line 12, and a plas...

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Abstract

This application provides a whole-liver type bioartificial liver system dedicated pipeline, including a plasma separation pipeline, a blood storage tank, a blood storage tank drainage line, a pre-hepatic pipeline, a post-hepatic pipeline and a whole liver perfusion device; The pipeline includes a plasma separation catheter and a plasma separation pump, and the plasma separation catheter is connected with the blood storage tank to input recipient plasma; the blood storage tank drainage line includes a blood drainage catheter and a blood drainage pump, and the prehepatic pipeline includes a prehepatic catheter, liver The posterior pipeline includes the retrohepatic catheter, the blood drainage catheter, the prehepatic catheter and the retrohepatic catheter are connected sequentially in the direction from the output end of the blood storage tank to the input end, and the whole liver perfusion device is set between the anterior hepatic catheter and the retrohepatic catheter; The blood storage tank lead tube, pre-hepatic line, post-hepatic line and whole liver perfusion device constitute an extracorporeal liver perfusion cycle, and the plasma separation line and extracorporeal liver perfusion cycle are connected in parallel through the blood storage tank. The special pipeline provided by the present invention is adapted to the whole-liver bioartificial liver system, can realize the docking of various equipment in the system, and is easy to install.

Description

technical field [0001] This application relates to the field of medical devices, in particular to a dedicated pipeline for a whole-liver bioartificial liver support system. Background technique [0002] Bioartificial liver support system, as a "bridge therapy" method for liver failure waiting for liver source or liver self-regeneration, is a hot research topic at present. At present, artificial liver support system mainly includes biological artificial liver support system, non-biological artificial liver support There are three types of systemic and combined bioartificial liver support systems, among which the bioartificial liver is divided into hepatocyte type and whole liver type according to the different reactors. Based on the concept that the best artificial liver support is the liver itself, the whole liver bioreactor has a richer number of functional cells, the best three-dimensional cell conformation and better cost-effectiveness, and the clinical application has su...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M1/14A61M1/36
CPCA61M1/14A61M1/3621
Inventor 高毅薛巍松李阳
Owner GUANGDONG UNISUN BIOTECHNOLOGY CO LTD
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