Medical acrylate pressure-sensitive adhesive and preparation method thereof

Abstract

The invention belongs to the field of new materials, particularly discloses a medical acrylate pressure-sensitive adhesive and a preparation method thereof, and provides the following scheme aiming at the problem of sensitization caused by the fact that residual monomers of an existing medical pressure-sensitive adhesive cannot be eliminated. The adhesive is prepared from the following raw materials in parts by weight: 60-90 parts of butyl acrylate, 4-10 parts of ethyl acrylate, 4-20 parts of vinyl acetate, 1-5 parts of acrylic acid, 0.2-0.6 part of initiator, 0.15-0.4 part of a buffer agent and 50-80 parts of water. The method comprises the following steps: adding the rest weight of water, the rest weight of initiator and half weight of pre-emulsion into a four-neck flask provided with a stirrer, a thermometer, a reflux condensing tube, a dropping funnel and a nitrogen inlet, slowly stirring, heating to 80 DEG C, and reacting for 0.5 hour. The medical acrylate pressure-sensitive adhesive provided by the invention has the advantages of no monomer residue, good skin compatibility and excellent adhesive property.

Description

technical field [0001] The invention relates to the technical field of new materials, in particular to a medical acrylate pressure-sensitive adhesive and a preparation method thereof. Background technique [0002] Medical pressure-sensitive adhesives require polymers with no monomer residues and good skin compatibility. Existing medical pressure-sensitive adhesives are generally divided into polyisobutylene pressure-sensitive adhesives, silicone rubber pressure-sensitive adhesives, and acrylate pressure-sensitive adhesives. Among them, the polyisobutylene pressure-sensitive adhesive needs to add additional tackifying resin to improve the viscosity due to its complex components, so its skin compatibility is poor and phase separation is prone to occur. The viscosity of silicone rubber pressure-sensitive adhesive depends on its functional group silanol, but the content is not easy to control, and it is easy to affect the degree of crosslinking, causing cold flow, easy residue ...

AI Technical Summary

Problems solved by technology

Among them, polyisobutylene pressure-sensitive adhesives need to add additional tackifying resin to improve the viscosity due to their complex components, so their skin compatibility is poor and phase separation is prone to occur

The viscosity of silicone rubber pressure-sensitive adhesive depends on its functional group silanol, but the content is not easy to control, and it is easy to affect the degree of crosslinking, resulting in cold flow, easy residue on the skin, and high sensitization

There are three main problems in the existing acrylate pressure-sensitive adhesives: 1. Viscosity control problem

It is impossible to accurately adjust the viscosity and cohesion of the pressure-sensitive adhesive through the polymerization process to achieve the best use of the skin, resulting in the inability to complete the paste within the required time or after the paste cannot be easily removed, resulting in skin tearing pain; 2. Skin High sensitization

Because the monomer residual rate cannot be effectively reduced during the synthesis process, the residual monomers of small molecules cause skin sensitivity, redness and swelling; 3. Residual problems on the skin surface