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Multi-modal brain image data processing method and device, equipment and storage medium

A data processing and brain imaging technology, applied in character and pattern recognition, recognition of medical/anatomical patterns, instruments, etc., can solve the problems of ineffective use of complementary information and high reliability of biomarkers

Active Publication Date: 2021-06-18
XIDIAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, biomarkers of Crohn's disease based on single-modal brain imaging often cannot effectively utilize the complementary information between different modalities, resulting in the reliability of biomarkers screened is not as high as multimodal biomarkers

Method used

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  • Multi-modal brain image data processing method and device, equipment and storage medium
  • Multi-modal brain image data processing method and device, equipment and storage medium
  • Multi-modal brain image data processing method and device, equipment and storage medium

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Experimental program
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Embodiment 1

[0051] See figure 1 and figure 2 , figure 1 It is a flow chart of a method for processing multimodal brain image data provided in this embodiment, figure 2 It is a schematic diagram of a method for processing multimodal brain image data provided in this embodiment. This embodiment discloses a method for processing multimodal brain image data, including:

[0052] Step 1. Obtain the multimodal brain imaging data set to be studied and the multimodal brain imaging data set to be verified.

[0053] In this embodiment, firstly, it is necessary to obtain the multimodal brain image data set to be studied and the multimodal brain image data set to be verified, and both the multimodal brain image data set to be studied and the multimodal brain image data set to be verified Including: resting state functional magnetic resonance imaging modality data set, diffusion tensor imaging modality data set and structural magnetic resonance imaging modality data set.

[0054] Specifically, the...

Embodiment 2

[0112] See Figure 5 , Figure 5 It is a schematic structural diagram of a device for multimodal brain image data processing provided in this embodiment. This embodiment discloses a device for processing multimodal brain image data, including:

[0113] Image acquisition module 1, used to acquire multimodal brain imaging data to be studied and multimodal brain imaging data to be verified;

[0114] The feature extraction module 2 is used to perform multivariate feature extraction on the multi-modal brain image data to be studied and the multi-modal brain image data to be verified, and correspondingly obtain the features to be mined and the features to be verified;

[0115] The biomarker extraction module 3 is used to perform feature selection on the features to be mined to obtain the target biomarkers, use the target biomarkers to construct a multi-core support vector machine classification model, and use the target biomarkers and the features to be verified to obtain the biom...

Embodiment 3

[0122] See Figure 6 , Figure 6 It is a schematic structural diagram of a device for processing multimodal brain image data provided in this embodiment. This embodiment discloses a device for processing multimodal brain image data, including: a processor, a communication interface, a memory, and a communication bus, wherein the processor, the communication interface, and the memory complete communication with each other through the communication bus;

[0123] memory for storing computer programs;

[0124] The processor is configured to implement the method steps in any one of the present embodiments when executing the computer program.

[0125] The device for processing multi-modal brain image data provided by the embodiment of the present invention can execute the above-mentioned method embodiment, and its implementation principle and technical effect are similar, and will not be repeated here.

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Abstract

The invention relates to a multi-modal brain image data processing method and device, equipment and a storage medium. The method comprises the steps: acquiring multi-modal brain image data to be researched and multi-modal brain image data to be verified; performing multivariate feature extraction on the to-be-researched multi-modal brain image data and the to-be-verified multi-modal brain image data to correspondingly obtain to-be-mined features and to-be-verified features; performing primary feature selection on the to-be-mined features to obtain first features; performing ultimate feature selection on the first feature to obtain a target biomarker and a feature index serial number thereof; constructing a multi-core support vector machine classification model by using the target biomarker; and obtaining a to-be-verified biomarker by using the feature index sequence number of the target biomarker and the to-be-verified feature, and obtaining a target verification result by using the to-be-verified biomarker and the multi-core support vector machine classification model. The multi-mode brain image data can be combined with unique information of each mode, and a more comprehensive angle is provided for understanding the Crohn disease brain image biomarkers.

Description

technical field [0001] The invention belongs to the field of medical equipment, and in particular relates to a method, device, equipment and storage medium for processing multimodal brain image data. Background technique [0002] Crohn's disease (CD) is a lifelong idiopathic and relapsing inflammatory bowel disease characterized by granulomatous inflammation of the intestinal wall from the mucosal to the serosal layers and also with enteral and extraintestinal manifestations. Crohn's disease appears comprehensive and heterogeneous in terms of site of onset and behavior, and may involve distinct healing and relapse events during the course of the disease. Brain-gut axis (BGA) and central nervous system dysfunction play an important role in the pathogenesis and development of Crohn's disease. Biomarkers refer to quantitative indicators of normal biological processes, pathogenic processes, or pharmacological responses to therapeutic interventions. Neuroimaging shifts the dise...

Claims

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Application Information

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IPC IPC(8): G06K9/62G06K9/46
CPCG06V10/443G06V2201/03G06F18/2411G06F18/25
Inventor 刘鹏杨光朴芮庆曾啸
Owner XIDIAN UNIV
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