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Preparation method of five-penis kidney-tonifying soft capsule

A soft capsule and kidney-tonifying technology, which is applied in the field of preparation of Wubian Bushen Soft Capsules, can solve the problems of slow disintegration of traditional Chinese medicine soft capsules, affect product quality, and easy delamination, achieve high content of active ingredients and avoid oil leakage of soft capsules , High bioavailability effect

Inactive Publication Date: 2021-06-22
锦州福寿堂医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented technology involves making pure Chinese medicines that contain various chemicals like ethanol (ethyl) , which makes them more easily absorbable from stomach than other herbs due to their higher concentrated flavorings compared with others' natural counterparts. By adding these components together, this new formulation becomes better at delivering its effectiveness over conventional methods such as pill/tablets and liquid dosage forms. Additionally, there are technical advantages related to controlling the manufacturing processes used while producing the final product containing an Active Ingredients Concentration called Capsaicin, along with added substances like glycerine soluble fatty acids, polysaccharides, polyvinols, carboxymethoxystanes, chlorophyllene oxide, hydroxypropyltriazole, thiocyanates, pigments, etc., resulting in improved stability and efficacy when taken internally without being swallowed again.

Problems solved by technology

Technological Problem addressed in this patents relates to improving the properties (quality) of existing veterinary drugs like dogs' saliva pill, cow milk foams, rutabies spermatozoys, frosty beef tallowings, lamb pills, licensed royalty fishery items, and various types of herbal mixtures containing these ingredients. However, current methods involve complicated steps involving multiple processes including grinding, mixing with liquid solvents before packaging them, compression forming into solid forms, and then freeze drying. These technical problem highlighted in the patented text involves finding ways to improve their performance without requiring complex procedures while maintaining stable qualities over time.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] (1) Weigh raw materials: curculigo 75g, Cynomorium cynomorium 75g, leek seed 50g, psoralen 100g, cinnamon 75g, medlar 125g, red ginseng 50g and Cnidium 75g herbal decoction pieces, mix well, add 70% ethanol 4375g was reflux extracted three times, the extraction temperature was 70°C, and each time was 3 hours, the extracts were combined, the ethanol was recovered, concentrated, and the concentrated solution A was obtained;

[0034] Add 62.5g of Epimedium and 50g of Achyranthes bidentata to 900g of water, extract three times, the extraction temperature is 100°C, 2 hours each time, combine the decoction, filter, the filtrate is concentrated to a thick paste with a relative density of 1.15-1.25 (60°C), add The concentration of 70% ethanol, which accounts for 3 times the mass of the thick ointment, is stirred for 10 minutes, airtight, and left to stand for 24 hours. The supernatant is absorbed and concentrated to obtain a concentrated solution B;

[0035] Combine concentrate...

Embodiment 2

[0049] (1) Weigh raw materials: curculigo 75g, Cynomorium cynomorium 75g, leek seed 50g, psoralen 100g, cinnamon 75g, medlar 125g, red ginseng 50g and Cnidium 75g herbal decoction pieces, mix well, add 70% ethanol 4375g was reflux extracted three times, the extraction temperature was 70°C, and each time was 3 hours, the extracts were combined, the ethanol was recovered, concentrated, and the concentrated solution A was obtained;

[0050] Add 62.5g of Epimedium and 50g of Achyranthes bidentata to 900g of water, extract three times, the extraction temperature is 100°C, 2 hours each time, combine the decoction, filter, the filtrate is concentrated to a thick paste with a relative density of 1.15-1.25 (60°C), add The concentration of 70% ethanol, which accounts for 3 times the mass of the thick ointment, is stirred for 10 minutes, airtight, and left to stand for 24 hours. The supernatant is absorbed and concentrated to obtain a concentrated solution B;

[0051] Combine concentrate...

Embodiment 3

[0065] (1) Weigh raw materials: curculigo 75g, Cynomorium cynomorium 75g, leek seed 50g, psoralen 100g, cinnamon 75g, medlar 125g, red ginseng 50g and Cnidium 75g herbal decoction pieces, mix well, add 70% ethanol 4375g was reflux extracted three times, the extraction temperature was 70°C, and each time was 3 hours, the extracts were combined, the ethanol was recovered, concentrated, and the concentrated solution A was obtained;

[0066] Add 62.5g of Epimedium and 50g of Achyranthes bidentata to 900g of water, extract three times, the extraction temperature is 100°C, 2 hours each time, combine the decoction, filter, the filtrate is concentrated to a thick paste with a relative density of 1.15-1.25 (60°C), add The concentration of 70% ethanol, which accounts for 3 times the mass of the thick ointment, is stirred for 10 minutes, airtight, and left to stand for 24 hours. The supernatant is absorbed and concentrated to obtain a concentrated solution B;

[0067] Combine concentrate...

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Abstract

The invention relates to a preparation method of a five-penis kidney-tonifying soft capsule, wherein the preparation method comprises the steps: taking Chinese wolfberry fruit, fructus psoraleae, Chinese chive seeds, fructus cnidii, cinnamon, cynomorium songaricum, red ginseng and rhizoma curculiginis, extracting with ethanol, and concentrating to obtain a concentrated solution A; taking herba epimedii and radix achyranthis bidentatae, and performing water extraction, alcohol precipitation and concentration to obtain a concentrated solution B; combining the concentrated solution A and the concentrated solution B, concentrating into silk paste, mixing with syngnathus powder and pilose antler powder, and crushing to obtain mixed medicine micro powder; extracting dog penis, sheep penis, donkey penis, cattle penis and mink penis with ethanol, and concentrating to obtain five-penis extracted oily extract; and adding the five-penis extracted oily extract and soybean oil into a mixing tank, adding the mixed medicine micro powder to obtain capsule contents, pressing the capsule contents and a gelatin solution to prepare gelatin pills, and carrying out shaping, pill washing and drying to obtain the five-penis kidney-tonifying soft capsule. The preparation method has the advantages that the preparation method is simple, the cost is low, the prepared capsule has a good disintegration effect, the capsule can be quickly disintegrated and absorbed by a human body after entering the stomach and intestine to reach an effective blood concentration, the content is high in utilization rate and absorption rate in vivo after being taken, and the stability is good during storage.

Description

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Claims

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Application Information

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Owner 锦州福寿堂医药科技有限公司