Plugging instrument
A device and wire technology, applied in the field of interventional medical devices, can solve problems such as invisible or poor visibility, tissue inflammation, and bad, and achieve the effects of reducing adverse effects on tissue, reducing clamping force, and slowing wear and tear.
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Embodiment 1
[0072] A occlusion device, including a occlusion frame, the occlusion frame is a set of 18 parallel iodized polylactic acid threads with a wire diameter of 0.40mm as the longitude thread and a set of 18 parallel polylactic acid fiber threads as the latitude The silk thread is pressed one by one, interlaced up and down to form a blocking frame. In the iodized polylactic acid thread, the mass percentage of iodine is 15%. The specification of each polylactic acid fiber thread is 50D / 72F.
[0073] The occlusion device of Example 1 was implanted in the septum of the heart of the Bama pig. During the implantation process, the occlusion device could be clearly identified under the DSA device. During the two follow-up visits of 1 month and 3 months after implantation, no adverse phenomena such as conduction block were found. One year after implantation, pathological section analysis of the occlusion device and surrounding tissues showed no obvious inflammation and foreign body react...
Embodiment 2
[0075] A occlusion device, including a occlusion frame, the occlusion frame is a set of 18 parallel polylactic acid threads with a wire diameter of 0.30mm as the longitude thread and a group of 36 parallel iodized polylactic acid fiber threads as the latitude The silk thread is pressed one by one, interlaced up and down to form a blocking frame. In the iodized polylactic acid thread, the mass percentage of iodine is 11%. The specification of each polylactic acid fiber thread is 80D / 72F.
[0076] The occlusion device of Example 2 was implanted in the septum of the heart of the Bama pig. During the implantation process, the occlusion device could be clearly identified under the DSA device. During the two follow-up visits of 1 month and 3 months after implantation, no adverse phenomena such as conduction block were found. One year after implantation, pathological section analysis of the occlusion device and surrounding tissues showed no obvious inflammation and foreign body rea...
Embodiment 3
[0078] A occlusion device, comprising a occlusion frame, the occlusion frame is a group of 18 parallel-arranged polyε-caprolactone wires with a wire diameter of 0.20mm as the longitude wires and a group of parallel-arranged mixed wires as the latitude wires, The mixed wires include polyε-caprolactone filaments and iodized polyε-caprolactone fibers arranged alternately and in parallel, wherein, there are 18 polyε-caprolactone filaments and 18 iodized polyε-caprolactone fibers The thread is 18 strands, which are woven one by one and staggered up and down to form a blocking frame. In the iodized polylactic acid thread, the mass percentage of iodine is 10%. In the mixed silk thread, the specification of each iodinated polyε-caprolactone fiber thread is 30D / 72F, and the silk diameter of the polyε-caprolactone thread is 0.40mm.
[0079] Soak the polyε-caprolactone silk thread (0.20mm and 0.40mm) and the iodized polyε-caprolactone fiber thread (30D / 72F, fastened with non-degradable ...
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Abstract
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