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Preparation method and application of skin moistening composition with anti-allergy and moisturizing effects

A composition and efficacy technology, which can be used in medical preparations containing active ingredients, skin care preparations, drug combinations, etc., can solve problems such as poor plant extract effects, and achieve plant extract safety, mild properties, and high content. Effect

Inactive Publication Date: 2021-09-17
江苏巴帝恩生物科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to improve the problem of poor effect of plant extracts in the prior art, a preparation method and application of an emollient composition with soothing and moisturizing effects is proposed. The fermentation liquid is obtained after microbial fermentation with yeast, and the The fermented liquid is used as the extraction solvent to extract and purify citrus fruit, aloe vera, golden chamomile, centella asiatica, grape skin, purslane, and white fungus

Method used

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  • Preparation method and application of skin moistening composition with anti-allergy and moisturizing effects
  • Preparation method and application of skin moistening composition with anti-allergy and moisturizing effects
  • Preparation method and application of skin moistening composition with anti-allergy and moisturizing effects

Examples

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Effect test

Embodiment 1

[0022] A preparation method and application of an emollient composition with soothing and moisturizing effects, the specific steps are as follows: figure 1 Shown:

[0023] 1) Inoculate Saccharomyces cerevisiae cultured on a shaker in advance into medium containing 1% peptone, 2% glucose, 0.04% potassium dihydrogen phosphate, 0.03% magnesium sulfate heptahydrate, and 0.3% sodium chloride, and ferment The conditions are: the pH range is 5.0-6.0, the fermentation temperature is 28°C, the shaker speed is 100rpm, and the fermentation time is 1d. After the fermented fermentation broth is sterilized, the filtrate is collected by filtration.

[0024] 2) Lycium citrus fruit extract, using methanol as the extractant, the ratio of solid to liquid is 1:3, reflux extraction at 50°C for 6 hours, after decompression and concentration to dryness, add 10% ethanol solution of 5 times the mass of the concentrated powder to dissolve, add The dichloromethane of equal volume of the solution is ex...

Embodiment 2

[0033] A preparation method and application of an emollient composition with soothing and moisturizing effects, the specific steps are as follows: figure 1 Shown:

[0034] 1) Inoculate Saccharomyces cerevisiae cultured on a shaker in advance into medium containing 2% peptone, 4% glucose, 0.05% potassium dihydrogen phosphate, 0.03% magnesium sulfate heptahydrate, and 0.5% sodium chloride, and ferment The conditions are: the pH range is 5.0-6.0, the fermentation temperature is 30° C., the shaker speed is 130 rpm, and the fermentation time is 1.5 days. After the fermented fermentation broth is sterilized, the filtrate is collected by filtration.

[0035] 2) Lycium citrus fruit extract, using methanol as the extractant, the ratio of solid to liquid is 1:5, reflux extraction at 50°C for 6 hours, concentrated under reduced pressure to dryness, add 10% ethanol solution of 5 times the mass of the concentrated powder to dissolve, add The dichloromethane of equal volume of the solutio...

Embodiment 3

[0044] A preparation method and application of an emollient composition with soothing and moisturizing effects, the specific steps are as follows: figure 1 Shown:

[0045] 1) Inoculate Saccharomyces cerevisiae cultured on a shaker in advance into medium containing 2% peptone, 4% glucose, 0.05% potassium dihydrogen phosphate, 0.05% magnesium sulfate heptahydrate, and 0.5% sodium chloride, and ferment The conditions are: the pH range is 5.5-6.5, the fermentation temperature is 30° C., the shaker speed is 130 rpm, and the fermentation time is 1.5 days. After the fermented fermentation broth is sterilized, the filtrate is collected by filtration.

[0046] 2) Lycium citrus fruit extract, using methanol as the extractant, the ratio of solid to liquid is 1:5, reflux extraction at 60°C for 6 hours, concentrated under reduced pressure to dryness, add 5 times the mass of the concentrated powder to dissolve in 20% ethanol solution, add The dichloromethane of the equal volume of the sol...

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Abstract

The invention provides a preparation method and application of a skin moistening composition with anti-allergy and moisturizing effects, and belongs to the technical field of plant extraction, microbial fermentation and cosmetics. The preparation method comprises the following steps that saccharomycetes is subjected to microbial fermentation to obtain fermentation liquid, the fermentation liquid is used as an extraction solvent, and Chinese wolfberry fruits, aloe, chrysanthellum indicum, centella asiatica, grape skin, purslane and tremella fuciformis are correspondingly extracted and purified; and the fermentation liquid is used as a solvent, the plant extract is added according to a certain proportion, a proper amount of butanediol is added, mixing, stirring and dissolving are carried out completely, sterilizing is carried out, and sequentially filtering is carried out through filter elements with the pore diameters of 3 microns, 1 micron and 0.22 micron to obtain the product. A drop of water is not additionally added in the product, and the yeast filtrate is completely used as a solvent; and the skin moistening composition is richer in nutrition and more powerful in effect, is rich in various amino acids, polysaccharides, vitamins and plant extract essence, can nourish and care skin, resist inflammation, relieve and moisturize, and is a very excellent cosmetic raw material.

Description

technical field [0001] The invention relates to the technical fields of plant extraction, microbial fermentation and cosmetics, in particular to a preparation method and application of a moisturizing composition with soothing and moisturizing effects. Background technique [0002] In recent years, China's economy has developed rapidly, and people's living standards have improved significantly. However, the environment has been destroyed, the atmosphere has been polluted, and the number of patients with skin allergies has increased sharply. In the current cosmetics market, anti-allergic ingredients are mainly chemically synthesized, which can easily cause skin sensitivity and even inflammation. favorite. [0003] The current technology is mainly to simply extract the plants and use them directly. Most of the plant extracts produced by this method have no practical effect. . Contents of the invention [0004] In order to improve the problem of poor effect of plant extract...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/9789A61K8/9728A61K8/34A61Q19/00A61P37/08
CPCA61K8/9794A61K8/9789A61K8/9728A61K8/345A61Q19/00A61Q19/005A61P37/08A61K2800/85A61K2800/84A61K2800/5922
Inventor 陈秀玉朴寅纪金庚泰詹柱刘晓磊丁冲冲何沪宝郑海兵赵治勇
Owner 江苏巴帝恩生物科技有限公司
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