Application of recombinant humanized collagen and related composition and preparation method thereof
A collagen and humanized technology, applied in the field of biomedicine, can solve the problems of low efficacy, drug resistance of children's skin, and adverse effects of children, and achieve the effects of accelerating relief, promoting restoration of luster, and reducing inflammatory reactions
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[0040] Embodiment 1: Recombinant humanized collagen treats eczema
[0041] 1. Recombinant humanized collagen relieves skin symptoms caused by eczema
[0042] 1.1 Establishment of experimental animal models (refer to "Specifications for the Preparation of Animal Models of Eczema (Draft)" to set up experimental models)
[0043] The 42 rats were divided into seven groups, namely control group, COL1 low concentration group, COL1 medium concentration group, COL1 high concentration group, COL2 low concentration group, COL2 medium concentration group and COL2 high concentration group, with 6 rats in each group. Divide the skin on the back of the rat into two parts, A and B, where part A is around the neck and part B is the back, and depilate it. The depilatory area of part A is about 2cm×2cm, and the depilatory area of part B is about 4cm×4cm . Prepare a solution of 2,4-dinitrochlorobenzene (DNCB) in acetone with a concentration of 7%, draw 100 μL with a pipette and apply it on...
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