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Embedded probiotic product with colonization effect and preparation process thereof

A preparation process and probiotic technology, which is applied in the field of embedded probiotic products and its preparation process, can solve the problems of weak intestinal colonization ability, etc., and achieve the effect of expanding the suitable population, improving the use effect, and improving the intestinal flora

Active Publication Date: 2021-10-22
青岛海益康健康科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Some strains have also been embedded, mainly to further reduce the damage of probiotics from gastric juice

Method used

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  • Embedded probiotic product with colonization effect and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] An embedded probiotic product with colonization effect, the probiotic product is made by embedding probiotics with a net-like adhesive substance as the inner wall material, and coating the outer layer with bacillus coagulans. Specifically, it is prepared from the following raw materials: 10% freeze-dried powder of probiotic bacteria strains, 3% purified water, 63% reticular adhesive substances and 24% bacillus coagulans liquid.

[0028] The probiotics in the freeze-dried powder of the probiotic strains are Bifidobacterium longum. The number of viable bacteria in the freeze-dried powder of the probiotic strains is ≥1.0×10 10 CFU / g.

[0029] The network adhesive substance is pectin.

[0030] The number of viable bacteria in the bacillus coagulans liquid is more than or equal to 1.0×10 8 CFU / g.

Embodiment 2

[0032] According to the following preparation process, the embedded probiotic product with colonization effect described in Example 1 was prepared:

[0033] (1) Adding pure water to the freeze-dried powder of probiotic bacteria strains, dissolving the freeze-dried powder of probiotic bacteria strains and making it appear in a non-Newtonian fluid state to obtain a probiotic bacteria ointment;

[0034] (2) Add the reticular adhesive substance into the probiotic ointment, mix evenly, and adjust the pH to 3.5 with lactic acid, then keep warm at -20°C, and freeze-dry for 24 hours to obtain freeze-dried powder A;

[0035] (3) Add reticular adhesive substance to freeze-dried powder A, mix well, and adjust pH to 3.5 with lactic acid, then keep warm at -20°C, freeze-dry for 24 hours, and obtain freeze-dried powder B;

[0036] (4) Control the temperature below 0°C, and apply the Bacillus coagulans liquid to the freeze-dried powder B by means of atomization spraying and stirring to obtai...

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Abstract

The invention discloses an embedded probiotic product with a colonization effect and a preparation process thereof. The probiotic product is prepared by embedding probiotics by taking a net-shaped adhesive substance as an inner-layer wall material and coating bacillus coagulans on the outer layer. The tolerance of the probiotics biologically embedded by the bacillus coagulans liquid in gastric juice and bile is further improved, and meanwhile, the bacillus coagulans absorbs moisture in the gastric juice, quickly propagates and grows in intestinal tracts, adapts to a low-pH environment in the growth process, consumes oxygen in the intestinal tracts and generates effective adhesive force, the mesh adhesive substances are decomposed, the probiotics are slowly released, and the planting capacity of the probiotics is greatly enhanced through the adhesive force and the better environment. The problem of colonization of traditional probiotics in intestinal tracts is solved. The suitable crowd of the probiotics is further expanded, the use effect is further improved, and further research and development of the probiotics are facilitated.

Description

technical field [0001] The invention relates to a probiotic product and a preparation process thereof, in particular to an embedded probiotic product with a colonization effect and a preparation process thereof. Background technique [0002] Recently, scientists have found that the intestinal flora and fecal flora are not equivalent, which reveals that the supplementation of probiotics in some people cannot colonize the intestines. Colonization refers to the combination of probiotics and host intestinal epithelial cells The process of growth and development is the premise of growth and development, and it is a physiological function that occurs after probiotics enter the intestinal tract. Due to the individual intestinal conditions, many people still cannot "retain" live bacteria in their intestines after taking a large amount of live probiotics, and the overall flora has no major changes, or only a small amount of changes. This is mainly because it is difficult for exogeno...

Claims

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Application Information

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IPC IPC(8): A61K9/19A61K35/741A61K35/742A61K35/745A61K35/747A61K35/744A61K47/36A61K47/46A61P1/00
CPCA61K9/19A61K35/741A61K35/742A61K35/745A61K35/747A61K35/744A61K47/36A61K47/46A61P1/00A61K2300/00
Inventor 李锡敏李营
Owner 青岛海益康健康科技有限公司
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