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Application of traditional Chinese medicine composition in preparation of medicine for treating autism

A composition and technology for autism, which can be used in drug combinations, pharmaceutical formulations, plant raw materials, etc., and can solve problems such as body weight changes and extrapyramidal reactions.

Pending Publication Date: 2021-10-22
SHIJIAZHUANG YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is currently no clinically specific drug for the treatment of ASD. Western medicine mainly uses human intervention and applied behavior analysis training, supplemented by drugs. Atypical antipsychotic drugs are usually used in drug treatment, but Western medicine often has There are certain side effects, and the lifelong nature of autism predestined long-term medication for patients, so adverse reactions such as weight changes and extrapyramidal reactions may occur

Method used

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  • Application of traditional Chinese medicine composition in preparation of medicine for treating autism
  • Application of traditional Chinese medicine composition in preparation of medicine for treating autism

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] The formula of raw material medicine is: jujube 300g, mulberry 300g, ganoderma lucidum 100g, lily 50g, hawthorn 100g, poria cocos 50g, tangerine peel 50g, chrysanthemum 100g, lotus leaf 50g;

[0050] Preparation:

[0051] (1) Take Chinese medicinal materials according to the prescription amount, and select them;

[0052] (2) Mix the above net-selected medicinal materials, make coarse powder, add 9 times the amount of water, soak for 1 hour, heat and decoct 2 times, the first time is 1.5 hours, the second time is 1 hour, filter, combine the filtrate, reduce Concentrate under pressure to a clear paste with a relative density of 1.20-1.25 during heat measurement at 60°C, add ethanol to adjust the concentration to 70% alcohol content, let stand below 4°C for 24 hours, filter, and recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell. Concentrate under reduced pressure to a liquid extract with a relative density of 1.02-1.06 when thermal...

Embodiment 2

[0055] The raw material medicine formula is: jujube 360g, mulberry 360g, ganoderma lucidum 100g, lily 60g, hawthorn 120g, poria cocos 60g, tangerine peel 60g, chrysanthemum 120g, lotus leaf 60g;

[0056] Preparation:

[0057] (1) Take Chinese medicinal materials according to the prescription amount, and select them;

[0058] (2) Mix the above net-selected medicinal materials, make coarse powder, add 9 times the amount of water, soak for 1 hour, heat and decoct 2 times, the first time is 1.5 hours, the second time is 1 hour, filter, combine the filtrate, reduce Concentrate under pressure to 60°C to a clear paste with a relative density of 1.20-1.25 during heat measurement, add 95% ethanol to adjust the concentration to 75%, let it stand below 4°C for 24 hours, filter, and recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell. Concentrate to a liquid extract with a relative density of 1.02-1.06 when thermally measured at 60°C, and set aside;...

Embodiment 3

[0061] The raw material medicine formula is: jujube 60g, mulberry 360g, ganoderma lucidum 20g, lily 60g, hawthorn 20g, poria cocos 60g, tangerine peel 10g, chrysanthemum 120g, lotus leaf 10g;

[0062] Preparation:

[0063] (1) Take Chinese medicinal materials according to the prescription amount, and select them;

[0064] (2) Mix the above net-selected medicinal materials, make coarse powder, add 9 times the amount of water, soak for 1 hour, heat and decoct 2 times, the first time is 1.5 hours, the second time is 1 hour, filter, combine the filtrate, reduce Concentrate under pressure to 60°C to a clear paste with a relative density of 1.20-1.25 during heat measurement, add 95% ethanol to adjust the concentration to 75%, let it stand below 4°C for 24 hours, filter, and recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell. Concentrate to a liquid extract with a relative density of 1.02-1.06 when thermally measured at 60°C, and set aside;

...

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Abstract

The invention provides application of a traditional Chinese medicine composition in preparation of a medicine for treating autism, the medicine is prepared from the following raw materials: wild jujube, mulberry, lucid ganoderma, lily, hawthorn, poria cocos, pericarpium citri reticulatae, chrysanthemum and lotus leaf, tests prove that the medicine treats both symptoms and root causes through medicine compatibility, can relieve and improve the autism symptom, is small in adverse reaction, and has wide application prospects.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to an application of a traditional Chinese medicine composition in the preparation of medicines for treating autism. Background technique [0002] The full name of autism is "autism spectrum disorder" (autism spectrum disorder, ASD), which is a generalized developmental disorder mental disease that occurs in early childhood and will accompany it throughout life. A very small number of patients can integrate into the mainstream society after adulthood, and most of them stay at home for a long time and need care for life, which brings a heavy burden to the family and society. Most of the research and practice focus on the young age, and there are few intervention methods and evidence-based research and practice for older children and adults with autism over the age of 13. [0003] According to the "Report on the Development of China's Autism Education...

Claims

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Application Information

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IPC IPC(8): A61K36/8967A61P25/00
CPCA61K36/725A61K36/605A61K36/074A61K36/8967A61K36/734A61K36/076A61K36/752A61K36/287A61K36/62A61P25/00A61K2236/331A61K2236/39A61K2236/53A61K2300/00Y02A50/30
Inventor 吴相君贾振华吴瑞
Owner SHIJIAZHUANG YILING PHARMA