Interventional renal artery sympathetic nerve activity detection system

Abstract

The invention provides an interventional renal artery sympathetic nerve activity detection system. The system comprises an interventional catheter, a various-blood detection sensor and blood analysis and detection equipment, an interventional end structure of the interventional catheter is communicated with a catheter, and chemical substances are conveyed to a preset position through the interventional end structure, wherein renal artery sympathetic nerves sense the concentration of the input chemical substances and then feed back through a RAAS system so as to secrete and form related blood to be detected; the various-blood detection sensor is arranged on the interventional catheter and close to the interventional end structure of the interventional catheter, and the various-blood detection sensor is used for detecting the blood to be detected to form detection signals; and the blood analysis and detection equipment is connected with the blood detection sensor and is used for receiving the detection signals and analyzing various signals of the blood to be detected to form corresponding physicochemical indexes reflecting the activity of the renal artery sympathetic nerves. The technical scheme has the beneficial effects that the activity of the renal artery sympathetic nerves can be accurately determined through the cooperative operation of the whole set of system.

Description

technical field [0001] The invention relates to the technical field of nerve detection, in particular to an interventional renal artery sympathetic nerve activity detection system. Background technique [0002] The RAAS system is the renin-angiotensin-aldosterone system. The classic RAAS includes: the juxtaglomerular cells of the glomerular afferent artery secrete renin, activate angiotensinogen produced in the liver to produce angiotensin I, and then convert enzymes in the pulmonary circulation to produce angiotensin II (ATII). ATII is the main effector substance of RAAS, acting on angiotensin II receptor 1, causing arteriole smooth muscle to contract, stimulating the adrenal cortex to secrete aldosterone, and increasing the secretion of norepinephrine through the positive feedback of the presynaptic membrane of the sympathetic nerve terminal , these effects can increase blood pressure. [0003] Although there is an analysis of the overall regulation results of the RAAS r...

AI Technical Summary

Problems solved by technology

[0005] The existing technology is to measure the activity of the renal artery sympathetic nerve by measuring the relevant physiological parameters after the ablation operation. The measurement conditions are strict, the measurement is difficult, the measurement process is complicated, and the feasibility is not large.

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