Chewing gum for promoting in-situ regeneration repair of soft and hard tissues of oral cavity and preparation method of chewing gum

Abstract

The invention provides chewing gum for promoting in-situ regeneration repair of soft and hard tissues of an oral cavity. The chewing gum comprises the following components in parts by weight: 1-30 parts of a regeneration repair material, 20 to 50 parts of gum base, 10 to 40 parts of a sweetening agent and 0.7 to 2 parts of glycerol, wherein the regeneration repair material is prepared from the following components in mole fraction: 42.0 to 47.0 percent of SiO2, 28.0 to 32.0 percent of CaO, 8.0 to 12.0 percent of SrO, 4.0 to 7.0 percent of Na2O, 4.0 to 6.0 percent of MgO and 1.5 to 3.5 percent of P2O5. According to the chewing gum and the preparation method thereof, the regeneration repair material, the gum base, erythritol, flavoring essence and the glycerol are proportioned and mixed in a specific mode and provided in the form of chewing gum, and the effect of in-situ regeneration repair of the soft and hard tissues of the oral cavity can be achieved at the same time. The invention further provides a preparation method of the chewing gum for promoting the in-situ regeneration repair of the soft and hard tissues of the oral cavity.

Description

technical field [0001] The invention belongs to the technical field of biomedical materials, and in particular relates to a chewing gum for promoting in-situ regeneration and repair of oral soft and hard tissues and a preparation method thereof. Background technique [0002] Caries and periodontal disease are the most common and frequently occurring oral diseases. The results of the "Fourth National Oral Health Epidemiological Survey" released in 2017 show that the oral health status of Chinese residents is mixed. 60-90% of children are suffering from dental caries. However, due to the conditions of oral health care, economic reasons and dental professional Due to the lack of technology and other reasons, most children cannot receive effective treatment. There are many reasons for dental caries, such as unhealthy diet, poor oral hygiene, excessive intake of sugar and various carbonated drinks. It will directly destroy the enamel, soften and loosen the minerals on the surfa...

AI Technical Summary

Problems solved by technology

The results of the "Fourth National Oral Health Epidemiological Survey" released in 2017 show that the oral health status of Chinese residents is mixed. 60-90% of children are suffering from dental caries. However, due to the conditions of oral health care, economic reasons and dental professional Due to the lack of technology and other reasons, most children cannot receive effective treatment

[0004] 1) The repair speed is slow, and it needs to be used for a long time

Moreover, when used as a toothpaste, the residence time in the oral cavity is very short, resulting in a very limited effect

[0005] 2) When the bioactive glass particles are in contact with the liquid, a rapid reaction occurs on the surface, causing a rapid increase in the local pH value, and the pH value can reach up to 13, forming a strong alkalinity and having certain cytotoxicity. bring some pain

[0006] For periodontal diseases, there are mainly conventional mouthwashes, which have a single function, mainly antibacterial and antibacterial, and do not have the function of regenerative repair

[0007] People with oral diseases are likely to suffer from dental caries and periodontal diseases at the same time, so products with a single function cannot meet the needs of the market

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