Pulse generating circuit, pulse generating device and pulse generation method

Abstract

The invention provides a pulse generating circuit, a pulse generating device and a pulse generation method. The pulse generating circuit comprises a charge storing unit, a voltage dividing unit and a pulse generating unit; the charge storing unit is electrically connected with a power supply module; the voltage dividing unit is electrically connected with the charge storing unit through an input end, electrically connected with a control module through an output end, and used for feeding back electric signals of the charge storing unit to the control module; the pulse generating device is electrically connected with the charge storing unit through an input end, electrically connected with the control module through a control end, and used for outputting pulses according to control signals of the control module; and the control signals are generated based on the electrical signals. The pulse generating circuit can ensure more uniform electric field distribution in cells and tissues to achieve more thorough tumor ablation effect, thereby reducing tumor recurrence; and meanwhile, the pulse generating circuit can greatly increase current density threshold value for causing muscle contraction so as to reduce muscle contraction strength to relieve pain of a patient in the treatment process and reduce electrode needle displacement, thereby ensuring more accurate control over the ablation area.

Description

technical field [0001] The present application relates to the technical field of signal generating devices, in particular, the present application relates to a pulse generating circuit, device and pulse generating method. Background technique [0002] Since IRE (Irreversible Electroporation) ablation of tumors was approved for clinical use, it has become more and more widely used and has achieved good therapeutic effects. However, with the deepening of clinical research, it is found that IRE has the following problems during ablation: due to the stimulation of pulsed electric fields, muscles and nerves will trigger action potentials, which will lead to muscle contraction during surgery, which will increase the pain of patients in clinical treatment. And it is easy to cause the electrode needle to shift, resulting in the inability to accurately control the ablation area; due to the uneven distribution of the electric field in the tissue, the local ablation of the tumor is not...

AI Technical Summary

Problems solved by technology

[0003] In view of the shortcomings of the existing methods, the present application proposes a pulse generating circuit, device and pulse generating method to solve the technical problems existing in the prior art due to the generation of action potentials and uneven electric field distribution

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