End-capped 3d cobalt (ii) porphyrin pof material and its preparation method and application

Abstract

The invention discloses a capped 3D cobalt (II) porphyrin POF material and its preparation method and application. (II), [4‑(4',4',5',5'‑tetramethyl‑1',3',2'‑dioxaborolanephenyl)]methane, potassium carbonate, Pd (PPh 3 ) 4 , the reaction solvent are added to the reactor together, the air in the reaction system is replaced by nitrogen, and the temperature is stirred to react; then the end-capping reagent is added, and the reaction is continued for 1.0~48.0 h; after the reaction is completed, filter, and the obtained solid is vacuum-dried after washing to obtain Capped 3D cobalt(II) porphyrin POF materials. The capped 3D cobalt(II) porphyrin POF material of the present invention catalyzes the method for preparing acetophenone and its derivatives through the selective oxidation of ethylbenzene and its derivatives, has the advantages of convenient operation, mild reaction conditions, etc., and is subjected to capping treatment It can significantly reduce the content of halogenated groups that are not conducive to the reaction in the POF material, thereby effectively improving the catalytic activity of the material, and the selectivity of catalytically generating aromatic ketones is high.

Description

technical field [0001] The invention belongs to the fields of organic chemical industry and fine organic synthesis, and in particular relates to an end-capped 3D cobalt (II) porphyrin POF material and a preparation method and application thereof. Background technique [0002] Acetophenone and its derivatives are an important class of fine chemical intermediates, which are widely used in the synthesis of fine chemical products such as medicines, pesticides, dyes, analytical detection reagents, and high-end intermediates (WO 201611034971; Bioorganic&Medicinal Chemistry Letters 2019,29: 525-528; Bioorganic Chemistry 2019, 82:360-377; ACS Applied Materials & Interfaces 2018, 10:44324-44335). At present, the synthesis of acetophenone and its derivatives mainly uses ethylbenzene, 1-phenethyl alcohol and styrene and their derivatives as raw materials, and is realized by oxidation reaction (US20190002487; CN 108947846; Molecular Catalysis 2019,469:27- 39; Organic Process Research &...

AI Technical Summary

Problems solved by technology

However, metalloporphyrins in a homogeneous state and surface-immobilized metalloporphyrins cannot effectively confine O 2 The disordered diffusion of free radicals during the oxidation of C-H bonds in hydrocarbons cannot achieve a significant increase in the selectivity of partial oxidation products

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