Traditional Chinese medicine nano-composite for stopping bleeding and resisting inflammation and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine nano-composite for stopping bleeding and resisting inflammation and a preparation method thereof. The traditional Chinese medicine nano-composite is prepared by compounding carboxymethyl chitosan, bletilla striata polysaccharide and dencichine. Firstly, the carboxymethyl chitosan is prepared through an enzymolysis reaction, then, the carboxymethyl chitosan, the bletilla striata polysaccharide and the dencichine are mixed for acidification treatment, neutralizing, washing, drying and sterilizing are carried out, and thus the traditional Chinese medicine nano-composite is obtained. The material has hemostasis and adhesion effects, instant gel can be formed, the material can be adhered to a wound surface to mechanically block a blood vessel crevasse, and meanwhile, the physical barrier can be used for isolating a wound to play a certain anti-adhesion action; the material contains bletilla striata and radix notoginseng and has the effects of stopping bleeding, resisting bacteria, diminishing swelling and promoting tissue regeneration, and the carboxymethyl chitosan is an important water-soluble chitosan derivative and has many medical effects such as promoting wound healing, stopping bleeding, inhibiting scars, easing pain and inhibiting bacteria; and the traditional Chinese medicine nano-composite is non-toxic and non-irritant and has hemostatic and antibacterial dual effects.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine nanocomposite for hemostasis and anti-inflammation and a preparation method thereof. Background technique [0002] Diabetic foot is a lesion in which the foot tissues of diabetic patients are destroyed due to factors such as diabetic vascular disease, neuropathy, and infection. If effective measures are not taken in time, it will cause foot ulceration and extremity necrosis, and even amputation is required in severe cases. In recent years, studies have found that Chinese medicine nanocomposites can effectively intervene and treat diabetic foot. Carboxymethyl chitosan is an important water-soluble chitosan derivative, which has many medical effects, such as promoting wound healing, hemostasis, inhibiting scars, analgesia and antibacterial effects, and is an excellent carrier for wound nanocomposites . [0003] The...

AI Technical Summary

Problems solved by technology

[0003] There are no home repair care products for diabetic foot in the domestic market. The existing repair care products are unsatisfactory in effect and have large side effects, which cannot meet the needs of diabetic foot patients.