Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Cardiac glycoside with anti-angiogenesis activity as well as preparation method and application of cardiac glycoside

An anti-angiogenesis and cardiac glycoside technology, applied in chemical instruments and methods, organic chemistry, anti-tumor drugs, etc., can solve the problem of difficult tumor treatment, and achieve the effect of significant social benefits and low cost.

Active Publication Date: 2022-01-25
LANZHOU UNIVERSITY
View PDF3 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although human beings have made great progress in tumors, the treatment of tumors is still a difficult problem to be overcome

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Cardiac glycoside with anti-angiogenesis activity as well as preparation method and application of cardiac glycoside
  • Cardiac glycoside with anti-angiogenesis activity as well as preparation method and application of cardiac glycoside
  • Cardiac glycoside with anti-angiogenesis activity as well as preparation method and application of cardiac glycoside

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0030] In order to make the object, technical solution and advantages of the present invention more clear, the present invention will be further described in detail below in conjunction with the examples. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the technical field of biochemical engineering, in particular to cardiac glycoside with anti-angiogenesis activity as well as a preparation method and application thereof. The cardiac glycoside with the anti-angiogenesis activity is a compound extracted and separated from digitalis lanceolata leaves. The compound has nano-molar concentration level proliferation inhibition activity on non-small cell lung cancer cells A549, cervical cancer cells Hela and breast cancer cells MCF-7. In addition, the compound can remarkably inhibit new angiogenesis on a chick embryo chorioallantoic membrane model, so that candidate drugs can be provided for developing novel anti-tumor angiogenesis drugs.

Description

technical field [0001] The invention relates to the technical field of biochemical industry, in particular to a cardiac glycoside with anti-angiogenesis activity and its preparation method and application. Background technique [0002] Tumor is a common disease that seriously threatens human health and life. The global incidence and mortality of cancer are rising rapidly. It has become the leading cause of human death and the most important obstacle to prolonging human life in the world in the 21st century. In order to reduce the morbidity and mortality of tumors, researchers from all over the world are making unremitting efforts for it. Although human beings have made great progress in tumors, the treatment of tumors is still a difficult problem to be overcome. [0003] Tumor growth depends on angiogenesis, which plays an extremely important role in the growth, invasion and metastasis of malignant tumors, and is also considered to be one of the main characteristics of canc...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07J17/00A61P35/00
CPCC07J17/005A61P35/00
Inventor 高坤杨红英陈建军
Owner LANZHOU UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com