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Application of Irpex lacteus in reducing blood fat

A technology of white rake tooth bacteria and blood lipid-lowering drugs, which is applied in the fields of application, medical preparations containing active ingredients, fungi, etc.

Pending Publication Date: 2022-03-01
GUANGXI UNIV FOR NATITIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there is no report on the effect of the fermented tea leaves and the effect of the albicans on hyperlipidemia.

Method used

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  • Application of Irpex lacteus in reducing blood fat
  • Application of Irpex lacteus in reducing blood fat

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Example 1. Research on lowering blood lipids of the metabolic composition of white rake tooth bacteria

[0025] 1. Preparation of the metabolic composition of white rake tooth bacteria

[0026] (1) Get 8 pine logs with a diameter of 10 centimeters, dry at room temperature, connect the strains on the pine bark, and cultivate them statically under 42% humidity. The cultivation temperature is 25 ° C. , take out the fruit body, add 500mL distilled water, extract at 100°C for 10 minutes, filter to obtain the filtrate, repeat the above extraction steps, extract three times, combine the filtrate to obtain filtrate A, take part of the filtrate A and concentrate it into fruit body extract (A1), Another part of the filtrate A is used to make the metabolic composition (A2) of R. albicans.

[0027] (2) Preparation of the seed liquid of the bacterium: take 35g of potato glucose extract powder, dissolve in 1000mL of distilled water, and sterilize under high pressure at 121°C for 30 ...

Embodiment 2

[0063] Embodiment 2, research on the hypolipidemic effect of fermented liquid of white rake-tooth bacterium

[0064] The tea leaves used in the following examples were purchased from Nanfang Tea Factory in Hengxian County, Guangxi.

[0065] One, the preparation of fermented liquid of white rake tooth bacteria

[0066] 1. Fermented liquid of white rake tooth bacteria (including green tea)

[0067] (1) Take 1kg of green tea, add 20L of distilled water, extract at 100°C for 15 minutes, filter, and sterilize at 121°C for 30 minutes to make green tea water culture medium for later use.

[0068] (2) Preparation of the seed solution of the bacterium: take 35g of the potato glucose medium, dissolve in 1000mL of distilled water, and sterilize at 121°C for 30 minutes for later use; under aseptic conditions, pick an appropriate amount of the bacterium and inoculate the seed solution in 25°C and 155r / min shaker for 3 days to obtain the seed liquid of R. albicans.

[0069] (3) Under ase...

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Abstract

The invention discloses an irpex lacteus metabolism composition and the blood fat reducing activity of irpex lacteus tea fermentation liquor. Accordingly, the inventor also establishes a corresponding Irpex lacteus metabolism composition and a preparation method of Irpex lacteus tea fermentation liquor. A further research shows that the Irpex lacteus metabolism composition and the Irpex lacteus tea fermentation liquor can significantly reduce the content of blood fat indexes TG, TC and LDL-C of hyperlipidemia model mice, significantly improve the HDL-C level, and have a good blood fat reducing effect on hyperlipidemia. Therefore, the Irpex lacteus metabolism composition and the Irpex lacteus tea have high application value in the aspect of reducing blood fat, a theoretical basis is provided for deep research and development of the Irpex lacteus and the Irpex lacteus tea, and a new product capable of improving or treating hyperlipidemia is expected to be developed according to the theoretical basis.

Description

technical field [0001] The invention belongs to the technical field of white rake tooth fungus, in particular to the application of white rake tooth fungus for lowering blood fat. Background technique [0002] Irpex lacteus belongs to Basidiomycota, Agaricaceae, Polyporacea, Polyporaceae, and Irpex lacteus; it is mainly distributed in Changbai Mountain, Jilin and other areas in China. The medicinal fungus mainly grows on the surface of the bark, grows flat, and the edge is rolled back and the surface is white, with slender hairs. The fungus tube is 1-2mm long and the hole surface is white or egg yolk white. It is parasitic on Pinus tabulaeformis in wild state. It is dense white fluff on the medium, and the back of the medium is light yellow in the later stage. Albicans can enhance the mononuclear macrophage system and cellular immune function, promote the production of cytokines, enhance the humoral immune response, and can produce saponins and peptide chain substances that...

Claims

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Application Information

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IPC IPC(8): C12N1/14A61K36/07A61K36/82A61P3/06A23L31/00A23L33/00C12R1/645
CPCC12N1/14A23L31/00A23L33/00A61K36/07A61K36/82A61P3/06A23V2002/00A23V2200/3262
Inventor 杨立芳韦炎冶姜明国
Owner GUANGXI UNIV FOR NATITIES
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