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Composition for assisting in reducing blood fat, product containing composition and application

A technology for assisting blood lipid lowering and composition, applied in the field of natural medicine extracts, can solve the problems of shortened shelf life, moisture absorption of saponin extract, waste of raw materials, etc., and achieve good blood lipid lowering effect and improve blood lipid lowering effect.

Pending Publication Date: 2022-03-22
LIAONING HUANREN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In view of the above research background, the inventor believes that the active ingredients in ginseng and Panax notoginseng are mainly saponins, which contain polysaccharide groups, and the way of wet granulation is likely to cause the saponin extract to absorb moisture and shorten the shelf life
Dry granulation can well ensure the stability and activity of saponin components, but at the same time, polysaccharide groups will also adhere to the surface of the granulator during the dry rolling process, resulting in waste of raw materials

Method used

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  • Composition for assisting in reducing blood fat, product containing composition and application
  • Composition for assisting in reducing blood fat, product containing composition and application
  • Composition for assisting in reducing blood fat, product containing composition and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Example 1 Extraction process investigation

[0040] 1. Investigation on the extraction process of ginseng extract under the forest

[0041] 1. Raw material screening

[0042] Undergrowth ginseng with different growth years purchased from Liaoning and Jilin was selected respectively, and the content of saponins was determined. The most suitable raw materials of wild ginseng under the forest are selected.

[0043] Table 1 Screening of different varieties of ginseng raw materials

[0044]

[0045] Conclusion: Due to the Landmark Regulations of Liaoning Province, the content of wild ginseng under the forest should meet the total saponins ≥ 4.5%, the total content of ginsenoside Rg1 and ginsenoside Re should not be less than 0.61%, and the content of ginsenoside Rb1 should not be less than 0.41%. Then choose more than 15 years of forest ginseng as raw material.

[0046] 2. Extraction method screening

[0047] The wild ginseng under the forest with the same origin and...

Embodiment 2

[0162] In the present embodiment, an auxiliary blood lipid-lowering tablet is provided, and the preparation method of the tablet is as follows: take 250 g of ginseng freeze-dried powder (equivalent to 500 g of fresh ginseng), 250 g of Panax notoginseng extract (equivalent to freeze-dried ginseng Panax notoginseng 1000g), xylitol 85g, citric acid 10g mix evenly, dry granulation, granulation parameters are: feeding speed 35rpm, roller speed 6rpm, pressure 35bar, discharge speed 100rpm, sieve 0.8mm, again Add magnesium stearate 5g and mix uniformly, tablet, make tablet, 0.6g / sheet, make 1000 pieces.

Embodiment 3

[0164] In the present embodiment, an auxiliary blood lipid-lowering capsule is provided, and the preparation method of the capsule is as follows: take 250 g of ginseng freeze-dried powder (equivalent to 500 g of fresh ginseng), 250 g of Panax notoginseng extract (equivalent to freeze-dried Panax notoginseng 1000g) mixed evenly, dry granulation, granulation parameters are: feeding speed 35rpm, roller speed 6rpm, pressure 35bar, discharge speed 100rpm, sieve 0.8mm, pack into capsule shell, make capsules, 0.5g / granules, 1000 granules were prepared.

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Abstract

The invention relates to a composition for assisting in reducing blood fat, a product containing the composition and application. The understory ginseng and the pseudo-ginseng have a good auxiliary blood fat reducing effect, main active parts of the understory ginseng and the pseudo-ginseng are saponin components, and the probability of moisture absorption and degradation of the saponin active components can be effectively reduced by adopting dry granulation. In order to provide a blood fat reducing active component with better processing performance, the invention optimizes an extraction process of saponin components in the medicinal materials, and provides a composition which has better pharmacodynamic activity and is more suitable for dry granulation.

Description

technical field [0001] The invention belongs to the technical field of natural medicine extracts, and in particular relates to a composition for assisting in lowering blood fat, a product comprising the composition and a method for assisting in lowering blood fat. Background technique [0002] The information disclosed in this background section is only intended to increase the understanding of the general background of the present invention, and is not necessarily taken as an acknowledgment or any form of suggestion that the information constitutes the prior art already known to those skilled in the art. [0003] Ginseng is a natural tonic, which has the functions of treatment, health care, nourishing and strengthening the body. The main active ingredients include ginsenosides, polypeptides and polysaccharides. Injuries and antiviral drugs. [0004] Modern studies have proved that ginseng has a more prominent role in lowering blood lipids. Tan Bo et al. reported the effec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61K9/20A61K9/48A61P3/06A23L33/105
CPCA61K36/258A61K9/2018A61K9/1682A61P3/06A23L33/105A61K2236/333A61K2236/39A61K2236/51A23V2002/00A61K2300/00A23V2300/14A23V2300/10A23V2300/20A23V2200/326A23V2250/21A23V2250/2124A23V2250/6422A23V2250/032
Inventor 周书繁汪巍王辉张雪秦培红
Owner LIAONING HUANREN PHARMA
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