Toothpaste containing fibroin and preparation method thereof

A technology of silk protein and silk protein powder, which is applied in the field of toothpaste containing silk protein and its preparation, can solve the problems of toxicity and side effects, and achieve the effects of low cost, enhanced cleaning effect, and gum protection

Pending Publication Date: 2022-04-29
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In order to make toothpaste more effective, many inventions try to add various drugs to toothpaste, but these drugs often have toxic effects on the human body, especially after long-term use of drug toothpaste, the side effects are relatively large

Method used

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  • Toothpaste containing fibroin and preparation method thereof
  • Toothpaste containing fibroin and preparation method thereof
  • Toothpaste containing fibroin and preparation method thereof

Examples

Experimental program
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Effect test

preparation example Construction

[0044] Preparation of silk fibroin protein powder: take silkworm cocoon shells and wash them, and use saturated sodium carbonate solution to boil for 50 minutes to degumming. Dry the degummed cocoons and dissolve them with 8mol / L lithium bromide solution or calcium chloride solution. The solution is dialyzed to remove impurities, concentrated and then freeze-dried to obtain silk fibroin powder.

[0045] Preparation of sericin protein powder: take silkworm cocoon shells and wash them, and use deionized water to boil for 30 minutes to extract sericin solution. The sericin solution is concentrated and then freeze-dried to obtain sericin protein powder.

[0046] Prepare silk fibroin powder, colored cocoon sericin powder and white cocoon sericin powder respectively according to the above method, and dissolve the aforementioned three silk protein powders in water to prepare silk protein solution samples with a mass percentage concentration of 0.1%, namely Silk fibroin powder aqueo...

Embodiment 1

[0057] Taking the total amount of material as 100g, the toothpaste containing silk protein in the present embodiment comprises the following raw materials:

[0058] Sufficient cocoon shell, 20g of sorbitol, 45g of calcium hydrogen phosphate, 4.5g of polyethylene glycol, 2g of sodium lauryl sulfate, 2g of sodium lauroyl sarcosinate, 1g of essence, 0.5g of fiber Vegetarian Gum, 0.5g of Crinkle Carrageen, 0.2g of Monosodium Phosphate, 0.8g of Sodium Pyrophosphate, 0.5g of Sodium Monofluorophosphate, 0.05g of Methylparaben, 0.1g of Propylparaben .

[0059] The preparation method of above-mentioned toothpaste comprises the following steps:

[0060] (1) Take silkworm cocoon shells and wash them, and use saturated sodium carbonate solution to boil for 50 minutes for degumming. Dry the degummed cocoons and dissolve them with 8mol / L lithium bromide solution or calcium chloride solution. The solution is dialyzed to remove impurities, concentrated and then freeze-dried to obtain silk ...

Embodiment 2

[0065] The preparation process and the amount of materials added are the same as in Example 1, except that the amount of silk fibroin powder added in the toothpaste containing silk protein prepared in this example is 1 g.

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Abstract

The invention provides toothpaste containing fibroin and a preparation method of the toothpaste. The toothpaste is prepared from the following components: fibroin powder, sorbitol, calcium hydrogen phosphate, polyethylene glycol, sodium lauryl sulfate, sodium lauroyl sarcosinate, essence, cellulose gum, chondrus crispus, sodium dihydrogen phosphate, sodium pyrophosphate, sodium monofluorophosphate, methylparaben and propyl hydroxybenzoate. Fibroin is an animal-derived natural material which is easy to obtain and has a great beauty value. According to the preparation method, the fibroin is taken as a main functional component, the abrasive, the adhesive, the humectant, the surfactant, the deionized water, a small amount of essence and the like are added, stirring and degassing are performed, and finally the toothpaste containing the fibroin is obtained. The toothpaste disclosed by the invention is fine and smooth in mouth feel, and has the effects of protecting teeth for a long time, relieving periodontitis, nourishing gingiva and improving periodontal health.

Description

technical field [0001] The invention belongs to the technical field of daily necessities, and in particular relates to a silk protein-containing toothpaste and a preparation method thereof. Background technique [0002] Toothpaste is a necessity used in daily oral care in people's lives. Toothpaste is usually in the form of a gel, which removes the dirt adhering to the teeth by increasing the mechanical friction between the toothbrush and the teeth. With the development of medicine and material science, toothpaste has gradually improved from the previous single friction and decontamination effect to today's multi-functional product with anti-cavity effect, strong root and tooth health, and its taste is becoming more and more delicate, which makes the human body feel The stimulation is getting smaller and smaller. Moreover, the materials and formulations of toothpaste are still in continuous development. Nowadays, many toothpastes are also beginning to try to add various n...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/64A61K8/24A61Q11/00A61P1/02
CPCA61K8/64A61K8/24A61Q11/00A61P1/02A61K2800/28
Inventor 杨明英汪晔铖王捷
Owner ZHEJIANG UNIV
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