Unlock instant, AI-driven research and patent intelligence for your innovation.

Interferon spray

A technology of interferon and spray, applied in the field of biopharmaceutical preparations, to achieve the effect of increasing deposition rate, high stability, and prolonging spray time

Pending Publication Date: 2022-05-13
SHENZHEN SCIPROGEN BIO PHARMA
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the physical and chemical factors of the ingredients in the preparation interact with each other, and it is a challenge to develop an interferon spray with good atomization performance and stability

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Interferon spray
  • Interferon spray
  • Interferon spray

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Preparation of embodiment 1 interferon spray composition

[0026] Prepare the prescription: see Table 1.

[0027] Preparation method: mix each component according to the prescription in Table 1, and make up 100ml with water for injection.

[0028] The interferon spray composition prescription of 100ml of table 1

[0029]

Embodiment 2

[0030] Preparation of embodiment 2 interferon spray composition (comparative example)

[0031] Prepare the prescription: see Table 2.

[0032] Preparation method: mix each component according to the prescription in Table 2, and make up 100ml with water for injection.

[0033] The interferon spray composition prescription of table 2 100ml

[0034]

Embodiment 3

[0035] Embodiment 3 surface tension test

[0036] The surface tension of the interferon spray composition prepared in Example 1 and Example 2 (comparative example) was detected by the pendant drop method, and the test results are shown in Table 3.

[0037] Table 3 surface tension

[0038] serial number Surface tension (mN / m) 1-1 51.82 1-2 50.76 1-3 53.41 1-4 55.45 1-5 50.18 2-1 65.83 2-2 50.93 2-3 49.22

[0039] The results showed that there were differences in the surface tension of spray compositions formulated with different formulations.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides an interferon spray. The interferon spray comprises an active ingredient interferon, a Tween surfactant, edetic acid or edetate, an osmotic pressure regulator, a pH regulator and a bacteriostatic agent. The interferon spray provided by the invention has good atomization performance and stability, and is especially suitable for pulmonary administration.

Description

technical field [0001] The invention relates to the field of biological pharmaceutical preparations, in particular to an interferon spray. Background technique [0002] Interferon is a non-specific viral immune signaling protein that exists in the human body. It is the earliest immune response factor for the body to viral infection. It has broad-spectrum antiviral activity and is mainly used for the prevention and treatment of viral diseases. Compared with traditional injection forms, interferon spray has the characteristics of less dosage and better curative effect. Interferon (IFN) aerosol inhalation is used for antiviral treatment in "Diagnosis and Treatment Program for Pneumonia Infected by Novel Coronavirus" (Trial Eighth Edition). [0003] The interferon spray is atomized into fine particles through the airflow, which can be absorbed through the respiratory tract. Among them, pulmonary administration is an ideal way of administration. By delivering the drug directly ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K38/21A61K9/12A61K47/26A61K47/18A61P11/00A61P31/14
CPCA61K38/212A61K9/0078A61K47/26A61K47/18A61P11/00A61P31/14A61K9/12
Inventor 吴园园程楚鸿王梦格曲啸黄健靳征娄竞
Owner SHENZHEN SCIPROGEN BIO PHARMA