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Application of trichosanthes kirilowii maxim, semen armeniacae amarae or compound extract thereof in preparation of cosmetics for repairing photoaging damage

A kind of trichosanthes extract, extract technology, applied in the field of Chinese medicine compound extract, can solve the problems such as unrecorded skin photoaging damage

Pending Publication Date: 2022-07-05
上海小方制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, there is no record of its specific use for photoaging damage of the skin in the prior art

Method used

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  • Application of trichosanthes kirilowii maxim, semen armeniacae amarae or compound extract thereof in preparation of cosmetics for repairing photoaging damage
  • Application of trichosanthes kirilowii maxim, semen armeniacae amarae or compound extract thereof in preparation of cosmetics for repairing photoaging damage
  • Application of trichosanthes kirilowii maxim, semen armeniacae amarae or compound extract thereof in preparation of cosmetics for repairing photoaging damage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Maximum Tolerated Concentration (MTC)

[0046] 2dpf wild-type AB lines were randomly selected in 6-well plates, and 30 zebrafish were treated in each well (experimental group). The drugs GL06, XR07 and SG357 were respectively added to the standard dilution water for fish farming (the concentrations are shown in Table 1), and the normal control group and the model control group were set at the same time, and the volume of each well was 3 mL. Except for the normal control group, the other experimental groups were irradiated with ultraviolet light to establish the zebrafish photoaging model. During sample processing, the number of dead zebrafish in each experimental group was counted and removed in time. After 1 day of treatment at 28°C, the MTC of the samples to photoaging model zebrafish was determined.

[0047] Table 1. The experimental results of the maximum tolerated concentration of the sample (n=30)

[0048]

[0049]

[0050] From the experimental results i...

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Abstract

The invention relates to application of trichosanthes kirilowii maxim, semen armeniacae amarae or compound extracts thereof in preparation of cosmetics for repairing light aging damage. According to the experiment provided by the invention, the trichosanthes kirilowii maxim and the semen armeniacae amarae are singly used or jointly used, and both have an anti-photoaging effect on a zebra fish photoinjury model. Moreover, after the two components are combined, the anti-photoaging effect has a synergistic effect, and the advantages of traditional Chinese medicine compatibility are better shown.

Description

technical field [0001] The present invention relates to the use of traditional Chinese medicine compound extracts, in particular, the present invention relates to the use of Gualou, bitter almond or their compound extracts in the preparation of cosmetics for repairing photoaging damage. Background technique [0002] With the improvement of people's living standards, the requirements for cosmetics have gradually increased from "covering" to "maintenance". However, there are various mechanisms of skin damage. In addition to aging with age, trauma, dryness, infection, immune inflammatory response, high and low temperature, sunlight / ultraviolet light, etc. will all cause damage to the skin. Damage to the skin caused by different reasons has different repair principles. Cosmetics are difficult to effectively repair skin damage caused by many reasons. [0003] Among the different causes of damage mentioned above, photoaging damage is caused by the combined action of natural agin...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61Q19/08
CPCA61K8/9789A61Q19/08A61K2800/5922
Inventor 王冰张宁邹纯朴方家辰
Owner 上海小方制药股份有限公司
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