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Method and device for rapidly screening amino acid sequences

An amino acid and sequence technology, applied in the field of rapid screening of amino acid sequences, can solve the problems of macromolecular protein feature calculation, low calculation efficiency of protein amino acid sequence, etc., and achieve the effect of rapid comparison

Pending Publication Date: 2022-07-05
医图生科(苏州)生命科学技术有限公司
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is currently no problem with the calculation of the characteristics of macromolecular proteins and the relatively low calculation efficiency of protein amino acid sequences.

Method used

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  • Method and device for rapidly screening amino acid sequences
  • Method and device for rapidly screening amino acid sequences
  • Method and device for rapidly screening amino acid sequences

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Embodiment Construction

[0017] The preferred embodiments of the present invention will be described in detail below with reference to the accompanying drawings. It should be understood that the preferred embodiments described below are only used to illustrate and explain the present invention, but not to limit the present invention.

[0018] figure 1 It is a flow chart of a method for realizing rapid screening of amino acid sequences provided in the embodiment of the present invention, such as figure 1 shown, including:

[0019] Step S101: Divide the target amino acid sequence L to obtain N target sub-amino acid sequences LN;

[0020] Step S102: By performing digital conversion processing on the N target sub-amino acid sequences LN respectively, N one-hot vector amino acid sequences composed of numbers are obtained, and the N one-hot vector amino acid sequences are aggregated to obtain the target amino acid sequence matrix M;

[0021] Step S103: Using the target amino acid sequence matrix M, calcu...

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Abstract

The invention discloses a method and device for rapidly screening amino acid sequences, and the method comprises the following steps: dividing a target amino acid sequence L to obtain N target sub-amino acid sequences LN; performing digital conversion processing on the N target sub-amino acid sequences LN to obtain N one-hot vector amino acid sequences formed by digits, and summarizing the N one-hot vector amino acid sequences to obtain a target amino acid sequence matrix M; respectively calculating composition, transfer, distribution CTD and sequence sequence combination number SOCN of the target amino acid sequence L by utilizing the target amino acid sequence matrix M; and screening an amino acid sequence similar to the characteristics of the target amino acid sequence L from a preset amino acid sequence library by utilizing the CTD and SOCN of the target amino acid sequence L.

Description

technical field [0001] The present invention relates to the technical field of protein amino acids, in particular to a method and device for realizing rapid screening of amino acid sequences. Background technique [0002] Sequence-based analysis and prediction are fundamental tasks of bioinformatics, which greatly advance the understanding of the sequence structure and function of DNA, RNA, and proteins. The rapid accumulation of sequences requires the development of new predictive models equally generally, depending on the availability of effective tools to support these efforts. Over the past few decades, high-throughput sequencing technologies have advanced dramatically and are widely used, generating unprecedented amounts of DNA, RNA, and protein sequence data. With the rapid accumulation of these data, effectively analyzing, mining and visualizing biological sequences has become a complex task. Among various computational solutions, machine learning methods are a popu...

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Application Information

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IPC IPC(8): G16B30/10G16B40/00G06K9/62
CPCG16B30/10G16B40/00G06F18/22
Inventor 李翛然陈宇综易爽马东强
Owner 医图生科(苏州)生命科学技术有限公司