Method for producing chlortetracycline premix finished product by one-step method

Abstract

The invention belongs to the technical field of chlortetracycline premix finished products, and particularly relates to a method for producing a chlortetracycline premix finished product through a one-step method. According to the finished product content, the fermentation broth titer, the filtrate titer, the fermentation broth dry matter content and the filtrate dry matter content to be produced in the batch, the calcium carbonate dosage is calculated through a finished product theoretical content calculation formula, calcium carbonate is added, after fermentation broth pretreatment, plate and frame filtration is conducted, a filter cake is granulated, and granulated particles enter a fluidized bed to be dried; the finished product particles enter an automatic packaging device to be packaged, meanwhile, sampling is carried out to detect the content, the content is compared with the theoretical content of the finished product, the chlortetracycline fermentation liquor can directly produce the chlortetracycline finished product, and the step of converting the chlortetracycline semi-finished product into the finished product is omitted.

Description

technical field [0001] The invention belongs to the technical field of chlortetracycline premix finished products, in particular to a method for producing chlortetracycline premix finished products by one-step method. Background technique [0002] The main component of chlortetracycline premix is ​​chlortetracycline calcium salt, which belongs to the tetracycline class and is widely used in animal husbandry. In the existing technology, calcium carbonate is generally used as an additive for the preparation of chlortetracycline premix. After fermentation, calcium carbonate is added to carry out complexation and dilution of the content. Due to the difference in the titer of the fermentation broth and the amount of added calcium carbonate, the content of the semi-finished products produced is high and low. Different and unstable, and chlortetracycline premix is ​​generally 10%, 15%, 20% content specifications, if you want to produce qualified finished products, you need to mix a...

AI Technical Summary

Problems solved by technology

In the existing process, calcium carbonate is generally used as an additive in the preparation of chlortetracycline premix. After the fermentation, calcium carbonate is added to complex and dilute the content. Due to the difference in the potency of the fermentation broth and the amount of calcium carbonate added, the content of the semi-finished product produced is high or low. Different and unstable, while aureomycin premix generally has content specifications of 10%, 15%, and 20%. If you want to produce qualified finished products, you need to mix and compound semi-finished products with different contents, and you need to store them in packaging bags and warehouses. Transshipment is required, the process is cumbersome, material and financial resources are wasted, and a part of the raw material of aureomycin fermentation broth will be wasted in each link