Compound saline algae capsule

The technology of compound salinal and salina is applied in the directions of capsule delivery, medical raw materials derived from algae, antidote, etc., which can solve the problems of large difference in dosage between salina and vitamin E, and no more reasonable formula, etc. To improve the immunity of the body, control the toxic and side effects of chemotherapy, and save animals.

Inactive Publication Date: 2007-06-13
天津市卫生防病中心
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0002] It is well known that the interaction between salinadin and vitamin E can improve immunity, antioxidant capacity and reduce the side effects of radiotherapy and chemothe...

Method used

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  • Compound saline algae capsule
  • Compound saline algae capsule
  • Compound saline algae capsule

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] As shown in Figure 1: Weigh 90g of salinadin, 135g of edible peanut oil, and 25g of vitamin E for preparation, pour 90g of salinadin and 50g of edible peanut oil into a large mortar and grind them evenly, then add 25g of vitamin E and 85g of edible peanut oil, and stir Evenly, you can get 250g liquid medicine.

[0021] The three comprehensive experiments of immune function detection, anti-oxidation ability and reducing the side effects of radiotherapy and chemotherapy were carried out on the mouse model. Second-level Blab / C mice were used for oral gavage for 30 days, and the gavage volume was 0.1ml / kg.bw ; Animal room conditions: SPF level animal room, temperature is 20-24 ℃, humidity is 40%-60%RH, its result is as follows:

[0022] 1. Immunological experiment, chicken erythrocyte phagocytosis index is 0.34, chicken erythrocyte phagocytosis rate is 7.67, NK cell activity is 57.3, carbon clearance phagocytosis index is 5.00, thymus ratio is 0.20%. Statistical results P<...

Embodiment 2

[0026] As shown in Figure 1: Weigh 90g of salinadin, 86g of edible peanut oil, and 74g of vitamin E for preparation. Pour 90g of salinadin and 50g of edible peanut oil into a large mortar and grind evenly, then add 74g of vitamin E and 36g of vegetable oil, and stir evenly to obtain 250g of liquid medicine.

[0027] Three comprehensive experiments were carried out on the mouse model, including immune function detection, anti-oxidation ability, and reduction of toxic and side effects of radiotherapy and chemotherapy. The experiment used second-level Blab / C mice, which were orally administered for 30 days, and the amount of intragastric administration was 0.1ml / kg. bw, animal room conditions: SPF level animal room, temperature is 20-24°C, humidity is 40%-60%RH, the results are as follows:

[0028] 1. Immunological experiment, chicken erythrocyte phagocytosis index is 0.34, chicken erythrocyte phagocytosis rate is 5.33, NK cell activity is 40.4, carbon clearance phagocytosis inde...

Embodiment 3

[0032] As shown in Figure 1: Weigh 45g of salinadin, 180g of edible peanut oil, and 25g of vitamin E for preparation. Pour 45g of salinadin and 50g of edible peanut oil into a large mortar and grind evenly, then add 25g of vitamin E and 130g of edible peanut oil, and stir evenly to obtain 250g of liquid medicine.

[0033] The three comprehensive experiments of immune function detection, anti-oxidation ability and reducing the side effects of radiotherapy and chemotherapy were carried out on the mouse model. Second-level Blab / C mice were used for oral gavage for 30 days, and the gavage volume was 0.1ml / kg.bw , Animal room conditions: SPF grade animal room, temperature is 20-24°C, humidity is 40%-60%RH, the results are as follows:

[0034] 1. Immunology experiment, chicken erythrocyte phagocytosis index is 0.20, chicken erythrocyte phagocytosis rate is 17.17, NK cell activity is 24.1, carbon clearance phagocytosis index is 2.88, thymus ratio is 0.23%. Statistical results P<0.05...

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Abstract

The invention relates to a compound Dunaliella salina capsule, wherein raw material comprises Dunaliella salina extract containing 33% of beta-carotene, vitamin E and edible peanut oil.

Description

technical field [0001] The invention relates to a compound salinadin capsule, in particular to a compound salinadin capsule obtained with a rational formula of salinadin and vitamin E by adopting an orthogonal design experiment method. Background technique [0002] It is well known that the interaction between salinadin and vitamin E can improve immunity, antioxidant capacity and reduce the side effects of radiotherapy and chemotherapy. / kg body weight-250mg / kg body weight, the formula of salinadin and vitamin E directly affects the above-mentioned functions, but there is no more reasonable formula at present. Contents of the invention [0003] The main purpose of the present invention is to overcome the above disadvantages and provide a compound salina capsule with a simple method, save time and animals, and can accurately find out the reasonable formula of salina neutralizing vitamin E. [0004] The technical solution adopted by the present invention to solve the techni...

Claims

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Application Information

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IPC IPC(8): A61K36/02A61K9/48A61P37/04A61P39/06
Inventor 李怡岚
Owner 天津市卫生防病中心
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