Hydrophilic ampholytic polymer
An amphoteric polymer, hydrophilic technology, applied to new hydrophilic amphoteric polymers, cleans, transports to the blood stream, learns or improves viscosity, can solve problems affecting drug absorption, and achieve improved adhesion , Antistatic adhesion effect
Inactive Publication Date: 2002-02-06
PMD控股公司
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- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Some compounds are known to affect the absorption of drugs by assisting the opening of these junctions
Method used
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Experimental program
Comparison scheme
Effect test
Embodiment 1
[0154] Preparation of HEMA / DMAPMA / MAA Amphoteric Polyelectrolytes in Solvent Mixtures
[0155] Reagent name
[0156] The solvent used was a mixture of two solvents ethyl acetate and cyclohexane. The surfactant used was a nonionic block copolymer surfactant sold under the tradename Hypermer by ICI Surfactants, Wilmington, DE.
Embodiment 2
[0158] Preparation of HEMA / DMAPMA / MAA Amphoteric Polyelectrolytes in Solvent Mixtures
[0159] Reagent name
Embodiment 3
[0161] Preparation of HEMA / DMAPMA / MAA / DMAAm Amphoteric Polyelectrolytes in Solvent Mixtures
[0162] Reagent name
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Abstract
A novel hydrophilic ampholytic polymer synthesized by reacting polymerizable amino and carboxy functional ethylenically unsaturated monomers, together with a non-ionic hydrophilic monomer, to provide a polymer having a glass transition temperature (Tg) above about 50 DEG C, and optionally hydrophobic monomer(s), and cross-linking monomer(s). The copolymer is precipitated from a polymerization media which includes a suitable organic solvent. The resulting copolymer is in the form of a fine powder, with submicron particle size. As such it is suitable for use as a thickener or rheology modifier in personal care formulations, such as shampoo, conditioner, and the like, as a bioadhesive, and for other pharmaceutical applications.
Description
Background of the invention [0001] The present invention relates to a new hydrophilic amphoteric polymer. Hydrophilic polymers can associate with water, have an affinity for water, and dissolve in water. Amphoteric polymers or amphoteric polyelectrolytes are polymers having both cationic and anionic groups. Uses of the polymers of the invention are as rheology modifiers in cationic and low pH (acidic) systems, as bioadhesives, as agents for removing bile salts and inhibiting enzymes, and as phosphate binding agents. agent. [0002] Amphoteric polymers are well known. For example, US Patent Nos. 5,286,827, 5,216,098, 5,130,391, 5,116,927 and 5,075,399 teach superabsorbent crosslinked zwitterionic pair copolymers in powder form for incorporation into infant diapers. The amphoteric nature of the polymer facilitates the absorption of urine. [0003] Polymers useful as rheology modifiers or thickeners include nonionic, cationic, anionic, and associative thickeners. Nonionic p...
Claims
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IPC IPC(8): A61K8/00A61K8/81A61K31/785A61K31/79A61K47/32A61P1/16A61P3/12A61P3/14A61P5/18A61P9/14A61P19/10A61P43/00A61Q5/02A61Q5/12A61Q11/00C08F220/00C08F220/28C08F220/34C08F220/56C08F226/00C08F226/06C09D157/12C11D3/20C11D3/37C11D17/08
CPCC08F220/34A61K2800/5428C08F226/06C08F220/56D06M15/263D06M15/267A61K8/8182C08F220/28A61Q5/02A61K47/32A61K8/8158A61Q5/12A61P1/16A61P3/12A61P3/14A61P5/18A61P9/14A61P19/10A61P43/00C08F220/20C08F220/04
Inventor R·加莱桂洛斯J·A·布德莱维奇J·A·奇阿莱里H·B·巴希纳Z·阿姆扎德
Owner PMD控股公司
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