Epimedium extract and its production method

An epimedium extract and extract technology, applied in the direction of drug combination, sugar derivatives, sugar derivatives, etc., can solve the problems of not having very ideal therapeutic drugs

Inactive Publication Date: 2003-12-10
JIANGSU KANGYUAN SUNSHINE PHARMA CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Osteoporosis is a common and frequently-occurring disease of middle-aged and elderly people, and there is no ideal drug for its treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] The preparation of embodiment 1 extract

[0068] Take 100kg of Epimedium medicinal material, decoct three times, add water 20 times the amount of medicinal material each time, decoct for 2 hours each time, combine the decoction liquid, filter, and concentrate the filtrate to a relative density of 1.10-1.13 (measured at 50°C) The thick ointment, let cool, add ethanol, make alcohol content reach 70%, leave standstill 24 hours, filter, and filtrate reclaims ethanol and concentrates to the thick ointment that relative density is 1.18-1.20 (50 ℃ is measured), let cool, Add distilled water (the same amount as the medicinal material) to dissolve, let stand at room temperature for about 4 hours, draw the supernatant, and pass through D 101 Type macroporous resin (diameter 10cm, long 100cm), elute with distilled water (3 times of column bed volume), flow velocity is 40ml / min, discard water eluent, then use 85% ethanol (4 times of column bed volume) ), collect the eluate, recove...

Embodiment 2

[0069] The preparation of embodiment 2 capsules

[0070] Epimedium Extract 309g

[0071] Starch 41g

[0072] Makes 1000 capsules

[0073] Preparation method: Take 309g of the total epimedium extract, add starch, mix well, put into capsules, and make 1000 capsules.

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Abstract

The epimedium extract which can be used for preparing medicine for curing osteoporosis is obtained by using Chinese medicinal materials epimedium through the processes of decocting in water, alcohol precipitation, macroporous resin adsorption, collecting eluent and concentrating eluent.

Description

Technical field: [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy. Especially relates to epimedium extract and its preparation process. Background technique: [0002] Osteoporosis is a common and frequently-occurring disease among middle-aged and elderly people, and there is no ideal drug for treatment at present. Epimedium is a traditional Chinese medicine for invigorating the kidney and yang in China. It has been used by the people for thousands of years. Its main chemical components are flavonoids, polysaccharides, lignans, alkaloids and oils. Current studies have shown that the effective substances are flavonoids. Currently, the research on the prevention and treatment of Epimedium for osteoporosis is mostly carried out at the level of compound and single herbs. To extract natural anti-disease drugs, they successively extracted flavonoids or derivatives with anti-osteoporosis effects from legumes. These compounds have estrog...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61P19/10C07H1/08C07H17/07G01N21/00G01N33/15
Inventor 张利民毋英杰张大军刘建璇
Owner JIANGSU KANGYUAN SUNSHINE PHARMA CO LTD
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