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Embedded material of austenitic stainless steel in medical use

A technology of austenitic stainless steel and stainless steel, applied in the direction of prosthesis, medical science, etc., can solve the problems affecting coronary stent restenosis, and achieve the effect of low cost, improved long-term use safety, and excellent combination of strength and toughness

Inactive Publication Date: 2004-08-11
INST OF METAL RESEARCH - CHINESE ACAD OF SCI
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Problems solved by technology

Recent studies have found that the side effects of nickel in stainless steel also affect restenosis after coronary stent surgery

Method used

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  • Embedded material of austenitic stainless steel in medical use
  • Embedded material of austenitic stainless steel in medical use

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Embodiment

[0025] According to the chemical composition range set by the present invention, 4 heats of steel were smelted in a vacuum induction furnace with a capacity of 25 kg, and the specific chemical composition is as shown in Table 1. These 4 furnaces of steel were poured into φ120×450 steel ingots respectively, and processed according to the above processing and heat treatment specifications.

[0026] All test specimens are sampled vertically along the rolling direction, and after the above heat treatment, the steel of the present invention is a single austenitic structure (such as figure 1 Shown), the measured mechanical properties are shown in Table 2. The anodic polarization curve of medical nickel-free austenitic stainless steel in equivalent physiological solution at 37°C was studied by electrochemical method. The results showed that the corrosion resistance of the new nickel-free stainless steel was better than that of medical 316L stainless steel, especially pitting propert...

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Abstract

A stainless austenite steel for medical implantation contains Cr(17-22 wt.%), Mn (12-20 wt.%), Mo (1-3 wt.%), Cu (0.5-1.5 wt.%), N (0.4-0.7 wt.%), Ni (0-0.02 wt.%), C (0-0.03 wt.%), Si (0-0.75 wt.%), S (0-0.01 wt.%), P (0-0.025 wt.%) and Fe (rest). It is smelted by vacuum induction furnace. Its advantage is very low content of toxic Ni.

Description

Technical field: [0001] The invention relates to a medical implant nickel-free austenitic stainless steel material and its application. Background technique: [0002] Medical implant stainless steel is the most widely used biomedical material, but it usually contains toxic nickel (Ni) element. For example, the medical 316L stainless steel commonly used clinically contains 10-14% nickel. After it is implanted into the human body, the passivation layer or protective layer on the surface will be damaged due to corrosion or wear, resulting in the metal nickel ions in it being very low. It is easy to accumulate in the tissues near the implant and affect the normal metabolism of the organism. Nickel is a potential sensitizing factor, which is teratogenic and carcinogenic to organisms. There have been reports on nickel allergy and carcinogenesis for a long time. Accumulation of nickel ions near implants in vivo can induce toxic effects, cell destruction and inflammatory responses...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/04C22C38/38
Inventor 任伊宾杨柯张炳春梁勇王亚庆肖克沈杨慧宾
Owner INST OF METAL RESEARCH - CHINESE ACAD OF SCI
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