Red sage root preparation for injection and its preparation method
A technology for injection preparations and salvia miltiorrhiza, applied in pharmaceutical formulations, medical preparations containing active ingredients, powder delivery, etc., can solve problems such as difficulty in dissolving
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Embodiment 1
[0036] 1. Prescription Danshen 1500g
[0037] 2. Extraction: Take the above-mentioned prescription medicinal materials, select them, wash them with deionized water, dry them, and crush them into coarse powder. Take the coarse powder of Danshen, put it in a supercritical fluid extractor, and extract it for 2 hours at an extraction pressure of 22 MPa and an extraction temperature of 45° C. to obtain a supercritical extract of Danshen. Take the supercritical extract of Salvia miltiorrhiza, dissolve it with an appropriate amount of ethanol, add it to the saturated HP-β-CD solution, stir at a constant temperature of 50°C until it becomes cloudy, continue stirring for 1.5h, put it in the refrigerator overnight, filter it with suction, and dry it at low temperature to obtain HP-β-CD inclusion compound powder; take the Danshen medicinal powder after supercritical extraction, decoct and extract three times with deionized water, combine the extracts, concentrate under reduced pressure t...
Embodiment 2
[0043] 1. Prescription Danshen 1500g
[0044] 2. Extraction: Take the above-mentioned prescription medicinal materials, select them, wash them with deionized water, dry them, and crush them into coarse powder. Take the coarse powder of Danshen, put it in a supercritical fluid extractor, and extract it for 2 hours at an extraction pressure of 22 MPa and an extraction temperature of 45° C. to obtain a supercritical extract of Danshen. Take the supercritical extract of Salvia miltiorrhiza, dissolve it with an appropriate amount of ethanol, add it to the saturated HP-β-CD solution, stir at a constant temperature of 50°C until it becomes cloudy, continue stirring for 1.5h, put it in the refrigerator overnight, filter it with suction, and dry it at low temperature to obtain HP-β-CD inclusion compound powder; take the Danshen medicinal powder after supercritical extraction, decoct and extract three times with deionized water, combine the extracts, concentrate under reduced pressure t...
Embodiment 3
[0050] 1. Prescription Danshen 1500g
[0051] 2. Extraction: Take the above-mentioned prescription medicinal materials, select them, wash them with deionized water, dry them, and crush them into coarse powder. Take the coarse powder of Danshen, put it in a supercritical fluid extractor, and extract it for 2 hours at an extraction pressure of 22 MPa and an extraction temperature of 45° C. to obtain a supercritical extract of Danshen. Take the supercritical extract of Salvia miltiorrhiza, dissolve it with an appropriate amount of ethanol, add it to the saturated HP-β-CD solution, stir at a constant temperature of 50°C until it becomes cloudy, continue stirring for 1.5h, put it in the refrigerator overnight, filter it with suction, and dry it at low temperature to obtain HP-β-CD inclusion compound powder; take the Danshen medicinal powder after supercritical extraction, decoct and extract three times with deionized water, combine the extracts, concentrate under reduced pressure t...
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