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Effervescent tablets for bone diseases and their preparation

An orthopaedic disease, effervescent tablet technology, applied in bone diseases, medical preparations containing active ingredients, pharmaceutical formulations, etc., can solve the problems of increasing the dosage and affecting the therapeutic effect of Xianling Gubao tablets, etc.

Inactive Publication Date: 2005-02-23
北京干露春科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although this process retains the fat-soluble and water-soluble active ingredients in Danshen medicinal materials, the use of Danshen medicinal materials as powder not only increases the dosage, but more importantly, the utilization of crude drugs directly affects the therapeutic effect of Xianling Gubao Tablets

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0089] (1) The raw materials and medicinal materials of 1000 tablets of Xianling Gubao Effervescent Tablets are as follows:

[0090] Epimedium 1167g Dipsacus 167g Salvia 83g

[0091] Anemarrhena 83g Psoralen 83g Rehmannia 83g

[0092] (2) Get the salvia miltiorrhiza medicinal material, pulverize, use 95% ethanol as solvent and extract twice with a multifunctional extractor; add 95% ethanol equivalent to 6 times of medicinal material weight each time; extract for the first time for 1 hour, and extract for the second time for 1 hour hours; combine the ethanol extracts, filter, and concentrate the filtrate to an extract whose relative density is 1.20 (50°C); The medicinal materials are mixed, and water is used as a solvent to extract three times with a multifunctional extractor; each time, water equivalent to 6 times the weight of the medicinal materials is added; the first extraction is 2 hours, the second extraction is 1 hour, and the third extraction is 0.5 hour...

Embodiment 2

[0105] (1) The raw materials and medicinal materials of 1000 tablets of Xianling Gubao Effervescent Tablets are as follows:

[0106] Epimedium 1050g Dipsacus 217g Salvia 100g

[0107] Anemarrhena 100g Psoralen 100g Rehmannia glutinosa 100g

[0108] (2) Get the medicinal material of Salvia miltiorrhiza, pulverize, and extract twice with a multifunctional extractor with 90% ethanol as a solvent; add 90% ethanol equivalent to 8 times the weight of the medicinal material each time; extract for the first time for 2 hours, and extract for the second time for 1 hours; combine the ethanol extracts, filter, and concentrate the filtrate to an extract whose relative density is 1.15 (50°C); The medicinal materials are mixed, and water is used as a solvent to extract three times with a multifunctional extractor; each time, water equivalent to 8 times the weight of the medicinal materials is added; the first extraction is 3 hours, the second extraction is 1 hour, and ...

Embodiment 3

[0120] (1) The raw materials and medicinal materials of 1000 tablets of Xianling Gubao Effervescent Tablets are as follows:

[0121] Epimedium 1245g Dipsacus 186g Salvia 83g

[0122] Anemarrhena 83g Psoralen 83g Rehmannia 83g

[0123] (2) Get the medicinal material of Salvia miltiorrhiza, pulverize, and extract twice with a multifunctional extractor with 80% ethanol as a solvent; add 80% ethanol equivalent to 10 times of the weight of the medicinal material each time; extract for the first time for 3 hours, and extract for the second time for 1 hours; combine the ethanol extracts, filter, and concentrate the filtrate to an extract whose relative density is 1.30 (50°C); The medicinal materials are mixed, and water is used as a solvent to extract three times with a multifunctional extractor; each time, water equivalent to 12 times the weight of the medicinal materials is added; the first extraction is 3 hours, the second extraction is 3 hours, and the thir...

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PUM

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Abstract

A Chinese medicine in the form of effervescent tablet for treating osteopathy is prepared from 6 Chinese-medicinal materials including epimedium, dipsacus root, red sage root, rehmannia root, etc through extracting, mixing with auxiliary and tabletting.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to an effervescent tablet for treating orthopedic diseases and a preparation method thereof. The effervescent tablet is also called Xianling Gubao effervescent tablet. technical background [0002] Xianling Gubao Tablets and Xianling Gubao Capsules are Chinese patent medicines currently on the market, which have the functions of nourishing the kidney and strengthening the body, strengthening bones and tendons, strengthening yang and strengthening bones, and enhancing emotions. Patent CN97107552 mentions that it is mainly used for the prevention and treatment of osteoporosis, fractures, osteoarthritis, aseptic necrosis of bone and menopausal syndrome. It has a good clinical therapeutic effect on primary osteoporosis, senile osteoporosis, aseptic bone necrosis, post-paraplegic osteoporosis and menopausal syndrome. The prescription contains six herbs ...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K9/46A61P19/08
Inventor 张晴龙
Owner 北京干露春科技有限公司
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