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Chinese medicine drippling pill preparation for promoting blood circulation and removing blood stasis, promoting Qi circulation and rilieving pain

A traditional Chinese medicine preparation and traditional Chinese medicine technology, which is applied in the direction of pill delivery, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of large dosage, slow drug effect, and low bioavailability

Active Publication Date: 2005-05-18
SHANDONG WOHUA PHARMACEUTICALS CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main performance is that some raw medicinal materials in the prescription are directly crushed into the medicine, the dosage is large, the bioavailability is low, and the efficacy of the medicine is slow.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0162] [Prescription]: Pueraria 500g, Hawthorn 400g, Salvia 400g, Panax notoginseng 20g, Woody fragrance 20g

[0163] [Preparation method] The above five medicinal materials, hawthorn, kudzu root and Panax notoginseng, were reflux extracted twice with 3 times the amount of each medicinal material, 1 hour for the first time, and 1 hour for the second time, combined with the ethanol extracts, and recovered ethanol, Filter and use the filtrate for later use. Extract three times of salvia miltiorrhiza, add 3 times the amount of 95% ethanol for the first time, reflux for 1 hour, filter, and recover the ethanol from the filtrate until it has no alcohol smell; add 3 times the amount of 80% ethanol for the second time, reflux for 1 hour, filter, and recover Ethanol; add water 3 times the amount of the medicinal material for the third time and reflux for 1 hour, filter, combine the filtrate, and concentrate under reduced pressure together with the above-mentioned standby filtrate to a ...

Embodiment 2

[0166] [Prescription]: Pueraria 800g, Hawthorn 800g, Salvia 800g, Panax notoginseng 60g, Woody fragrance 60g

[0167] [Preparation method] The above five medicinal materials, hawthorn, kudzu root, and Panax notoginseng, were reflux extracted twice with 40% ethanol at 10 times the amount of each medicinal material, the first time was 3 hours, and the second time was 3 hours, the alcohol extract was combined, and the ethanol was recovered. Filter and use the filtrate for later use. Salvia miltiorrhiza was extracted three times. For the first time, add 15 times the amount of 60% ethanol to reflux for 3 hours, filter, and recover the ethanol from the filtrate until it has no alcohol smell; add 15 times the amount of 20% ethanol to reflux for 3 hours, filter, and recover Ethanol; add 15 times the amount of medicinal material for the third time to reflux for 3 hours, filter, combine the filtrate, and concentrate under reduced pressure together with the above-mentioned standby filtra...

Embodiment 3

[0169] Pueraria 600g Hawthorn 600g Salvia 600g Notoginseng 40g Woody fragrance 40g

[0170][Preparation method] The above five medicinal materials, hawthorn, kudzu root, and Panax notoginseng, were reflux extracted twice with 80% ethanol with 8 times the amount of each medicinal material. Filter and use the filtrate for later use. Salvia miltiorrhiza was extracted three times. For the first time, add 12 times the amount of 95% ethanol to reflux for 1 hour, filter, and recover the ethanol from the filtrate until it has no alcohol smell; add 10 times the amount of 80% ethanol for the second time to reflux for 1 hour, filter, and recover Ethanol; add 10 times the amount of medicinal material for the third time to reflux for 1 hour, filter, combine the filtrate, and concentrate under reduced pressure together with the above-mentioned standby filtrate to a clear paste with a relative density of 1.08 (measured at 80°C). % ethanol was extracted three times with ethyl acetate, the ex...

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PUM

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Abstract

The present invention relates to a kind of Chinese medicine dripping pill preparation, named Xinkeshu dripping pill. The dripping pill preparation is prepared through the following technological steps: a. extracting haw, kudzu vine root and notoginseng with alcohol and filtering to obtain filtrate; b. extracting red sage with alcohol or water and filtering to obtain filtrate; c. merging the filtrate in the foregoing steps, concentration, extracting the concentrate with ethyl acetate with or without alcohol, concentration to obtain dense paste or drying to obtain powder; d. crushing aucklandia root, diacolation with alcohol and concentration to obtain dense paste; mixing the dense paste or powder obtained in the step c., the dense paste obtained in the step d. and polyglycol to obtain medicine liquid, and making dripping pill in a dripping pill machine.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine dripping pill preparation for promoting blood circulation, removing blood stasis, promoting qi and relieving pain. The dropping pill preparation is prepared by a new process. Background technique: [0002] Xinkeshu Tablets are developed by Shandong Wohua Medical Technology Co., Ltd. based on the prescriptions tested by famous doctors in the 1970s. It is now included in the Sixteenth Volume of Traditional Chinese Medicine Prescriptions (Protection Sub-volume) No. 24 in the "Drug Standards of the Ministry of Health of the People's Republic of China" Page, Xinkeshu Tablets is a national basic drug product, a national medical insurance product, and a national traditional Chinese medicine protection product. Xinkeshu tablet is composed of Danshen, kudzu root, hawthorn, panax notoginseng and woody incense, which has the effects of promoting b...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P3/06A61P9/06A61P9/10A61P9/12
Inventor 曾英姿
Owner SHANDONG WOHUA PHARMACEUTICALS CO LTD
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