Shengmai lyophilized powder for injection and its preparing method

A technology for freeze-dried powder and injection, which is applied in the direction of freeze-dried transportation, medical preparations containing active ingredients, powder transportation, etc. It can solve the problems of turbidity, preparation precipitation, easy hydrolysis, etc., and achieve stable and easy-to-control quality and long storage time. prolonged effect

Inactive Publication Date: 2005-10-05
魏秀华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the preparation is a light yellow liquid, and its active ingredients are unstable in water and easily hydrolyzed, which often causes the preparation to produce precipitation and turbidity.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0009] Shengmai for injection

[0010] 1. Formula

[0011] Red Ginseng 200g

[0012] Ophiopogon japonicus 624g

[0013] Schisandra 312g

[0014] Mannitol 200g

[0015] —————

[0016] A total of 1000 pieces were made

[0017] 2. Preparation method: crush the red ginseng into granules with the above three medicinal materials, add 75% ethanol to extract 4 to 5 times, each time for 2 hours, use thin layer chromatography to control the extraction end point, combine the extracts, refrigerate, and filter , recover ethanol and concentrate to a thick paste, add water for injection to 400ml, stir well, refrigerate, filter, and the filtrate is used for liquid preparation; Schisandra chinensis is used for collecting volatile oil by steam distillation, and the volatile oil is clathrated with hydroxypropyl cyclodextrin, and the dregs Add water and decoct twice, 40 minutes each time, filter, combine the filtrates, concentrate to a thick paste, add ethanol for alcohol precipitation twic...

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PUM

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Abstract

The present invention relates to a Shengmai freeze-dried power of injection and its preparation method. It is characterized by that its composition contains the Chinese medicine components of (wt%) 14-20% of red ginseng, 50-56% of ophiopogon tuber and 24-30% of schisandra fruit. Said invention has the functions of supplementing qi, nourishing yin, promoting blood circulation and stem desertion etc. Said invention also provides the concrete steps of its preparation method.

Description

field of invention [0001] The invention relates to a Shengmai freeze-dried powder for injection and a preparation method thereof, belonging to the field of traditional Chinese medicine preparations. Background of the invention [0002] Shengmai injection is improved from the classic ancient prescription "Shengmaisan", which is composed of ginseng, Ophiopogon japonicus and Schisandra chinensis. Ginseng is sweet and warm in nature and taste, enters the spleen and lungs, can greatly nourish the vitality, nourish the spleen and benefit qi and produce body fluid; Ophiopogon japonicus tastes slightly bitter and slightly cold in nature, returns to the heart, lung, and stomach meridian, can moisten the lungs, clear the heart, nourish the stomach and promote body fluid; the nature and taste of schisandra Sour and warm, enters the lung and kidney meridian, can restrain the lung, nourish the kidney, produce body fluid and astringent essence. Combined use of the three medicines has the...

Claims

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Application Information

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IPC IPC(8): A61K9/19A61P9/10
Inventor 魏秀华
Owner 魏秀华
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