Heat-clearing and phlegm-resolving medicine composition, preparation and use thereof
A heat-clearing and phlegm-resolving and composition technology is applied in the field of pharmaceutical compositions for clearing heat and removing phlegm, which can solve the problems of large clinical dosage, loss of effective components, long processing time, etc. High utilization effect
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Embodiment 1
[0030] Embodiment 1 Preparation of medicinal raw material extract extractum of the present invention
[0031] a. Cut 100g of fresh bamboo stalks of pink green bamboo into 2-5cm, put them in a 1000ml beaker, add 6 times the amount of water, control the temperature at 100°C, boil for 1.5 hours, filter the decoction, and add 4 Double the amount of water at 100°C, decoct for 1.0 hour, filter, combine the two filtrates, add distilled water to 1000ml to constant volume (each 1ml is equivalent to 0.1g of fresh Danzhu).
[0032] b. Concentrating the bamboo extract in step a (temperature below 80° C., specific gravity > 1.01) in a three-effect manner to obtain a bamboo leach concentrate. Process parameters: vapor pressure: ≤0.10Mpa; temperature: first effect: 75--85°C; second effect: 65--75°C; third effect: 55--65°C; vacuum degree: first effect: 0.020-0.040Mpa; Second effect: 0.040-0.060Mpa; Three effect: 0.060-0.080Mpa; Proportion of cream collection: 1.10-1.35 (40--80°C).
[0033] ...
Embodiment 2
[0037] Embodiment 2 Preparation of medicine bamboo extract extractum of the present invention
[0038] a. Cut 100g of fresh bamboo stalks of Elephant bamboo into 2-5cm, put it in a 1000ml beaker, add 6 times the amount of water, control the temperature at 100°C, boil for 1.5 hours, filter the decoction, and add 4 times the amount of filter residues respectively Water, temperature 100°C, decoct for 1.0 hour, filter, combine the two filtrates, add distilled water to 1000ml to constant volume (each 1ml is equivalent to 0.1g of fresh bamboo).
[0039]b. Add the bamboo extract into the decompression concentration tank, control the temperature at 60° C., and control the vacuum pressure at 0.08 Pa, and concentrate for 6 hours to obtain the bamboo extract concentrate;
[0040] c. Drying method: boiling drying.
[0041] The above comparative experiments show that the medicinal raw material extract of the present invention is not equal to the traditional roasted fresh bamboo leek, and ...
Embodiment 3
[0042] Embodiment 3 Preparation of pharmaceutical tablet of the present invention
[0043] Take an appropriate amount of starch and dextrin, mix them evenly, spray into the clear paste prepared in step b of Example 1, and granulate in one step, the spray frequency is 4HZ, the pressure is 0.12MPa, the material temperature is 40-50°C, the air inlet temperature is 75-85°C, and the air outlet The temperature is 70-75°C. The granules are mixed with 0.5% magnesium stearate, pressed into 1000 tablets, film-coated, subpackaged, and obtained.
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Abstract
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