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Dragon's blood gel preparation and its preparing method

A technology of gel preparation and dried blood, applied in the field of medicine, can solve the problems of inaccurate dosage, lack of suitable external preparations, waste of drugs, etc., and achieve the effects of advanced technology, convenient clinical application, and improved accuracy

Inactive Publication Date: 2006-03-22
FUKANGREN BIO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention provides an easy-to-use, accurate-dosed blood jelly preparation and a preparation method thereof, so as to solve the problem that there is no suitable external application for the treatment of bruises, bedsores, epidermal ulcers, chronic cervicitis, oral ulcers and other diseases in the prior art. preparations, and difficulties such as inaccurate dosing and drug waste

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0071] prescription:

[0072] Dried blood 200g

[0073] Hypromellose (4000Mpa.s) 8g

[0074] Carbomer 940 2.4g

[0075] Propylene glycol 167g

[0076] Methylparaben 0.15g

[0077] Appropriate amount of sodium hydroxide

[0078] Add water for injection to 1000g

[0079] Preparation:

[0080] Step 1: Ultrafinely pulverize dried blood to obtain ultrafine powder, and set aside;

[0081] Step 2: Separately disperse hydroxypropylmethylcellulose (4000Mpa.s) in hot water at 80-90°C, cool in the refrigerator overnight to make a clear solution, and disperse Carbomer 940 in 200ml of water, add enough Measure 1% sodium hydroxide solution to adjust the pH to 7, add purified water to about 400ml, dissolve methylparaben in propylene glycol, and mix the above solutions evenly to obtain a blank gel matrix.

[0082] Step 3: Slowly add the above superfine dried blood powder to the above blank matrix in stages, stir while adding, unt...

example 2

[0084] prescription:

[0085] Dried blood 200g

[0086] Cross-linked sodium polyacrylate 400 10g

[0087] Glycerin 50g

[0088] Methylparaben 0.15g

[0089] Ethylparaben 0.15g

[0090] Add water for injection to 1000g

[0091] Preparation:

[0092] Step 1: Ultrafinely pulverize dried blood to obtain ultrafine powder, and set aside;

[0093] Step 2: Take about 70% of distilled water at 60°C, sprinkle cross-linked sodium polyacrylate 400 on the liquid surface, let it swell for 24 hours to form a gel, and take methyl paraben and ethyl paraben in a mortar Add glycerin and grind well; gradually add the above gel, add water to about 800g, and mix well.

[0094] Step 3: Slowly add the above superfine dried blood powder to the above blank matrix in stages, stir while adding, until uniform, sterilize with circulating steam at 100°C for 30 minutes, and then pack it.

example 3

[0096] prescription:

[0097] Dried blood 200g

[0098] Propylene glycol 20g

[0099] Laurozone 20g

[0100] Triethanolamine 10g

[0101] Thimerosal 0.1g

[0102] Carbomer 10g

[0103] Add water for injection to 1000g

[0104] Preparation:

[0105] Step 1: Ultrafinely pulverize dried blood to obtain ultrafine powder, and set aside;

[0106] Step 2: Disperse Carbomer 940 in an appropriate amount of hot distilled water, place it for 24 hours to self-swell, adjust the pH to 6.5-7.5 with triethanolamine, take a small amount of distilled water to dissolve thimerosal, take propylene glycol and laurocapzone, and add the above ingredients respectively In the gel matrix, add distilled water to the full amount and mix well.

[0107] Step 3: Slowly add the above superfine dried blood powder to the above blank matrix in stages, stir while adding, until uniform, sterilize with circulating steam at 100°C for 30 minutes, and the...

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PUM

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Abstract

The present invention relates to a kind of dragoní»s blood gel preparation comprising dragoní»s blood in effective dosage as main medicine and gel mixed together. The preparation process includes dispersing polymer material as gel matrix inside solvent for full swelling, adding pH regulator to reasonable range, and adding preservative and permeation promoter to form gel; adding fine dragoní»s blood powder and mixing homogeneously. The dragoní»s blood gel preparation may be used in treating traumatic injury, bedsore, epidermis ulcer, chronic cervicitis and other diseases. The dragoní»s blood gel preparation has excellent skin adhesion, excellent spreading property, high permeation and high transdermal absorption effect.

Description

Technical field: [0001] The invention belongs to the field of medicine, and relates to an externally-used gel preparation with dried blood as the active ingredient of medicine and a preparation method thereof. The jellyfish gel preparation of the invention can be used for treating diseases such as bruises, bedsores, epidermal ulcers, chronic cervicitis, oral ulcers and the like. Background technique: [0002] Dracaena, also known as Qilin Drain, has been used as a precious traditional Chinese medicine for more than 1,500 years in my country. plant. Dried blood has the effects of reducing stasis and relieving pain, hemostasis and promoting granulation, and is used for traumatic injuries, internal injuries and bruises, and traumatic hemorrhage. Usually, it is ground or put into pills and taken orally, or ground and sprinkled or put into plasters for external use. [0003] The single dose and compound prescription of blood jellyfish have been applied in the fields of surgery,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61K9/00A61P17/02A61P1/02A61P15/00A61P29/00A61P19/00
Inventor 严轶东刘鸿林
Owner FUKANGREN BIO PHARMA
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