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Camellia-flower total flavone medicinal preparation, its preparing method and use

A pharmaceutical preparation, the technology of camellia, which is applied in the field of pharmaceutical preparations of total flavonoids of camellia and its preparation, can solve the undisclosed problems of the extraction and separation process of total flavonoids of camellia, the preparation method of pharmaceutical preparations, etc.

Inactive Publication Date: 2006-05-24
北京天新园医药科技开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above-mentioned literature reports the pharmacological effects of total flavonoids from camellia, it does not disclose any extraction and separation process of total flavonoids from camellia and the preparation method of related pharmaceutical preparations

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Take camellia, crush it, pass through a 40-mesh sieve, soak in 10 times the amount of water for half an hour, reflux extraction twice, each time for 1.0 hour, combine the extracts, and condense into a thick paste by rotating the scraping film below 50 °C.

Embodiment 2

[0071] Take camellias, crush them, pass through a 40-mesh sieve, soak in 6 times the amount of methanol for half an hour, and then reflux extraction twice for 0.5 hours each time.

Embodiment 3

[0073] Take camellias, crush them, pass through a 40-mesh sieve, soak them in 8 times the amount of 20% ethanol for half an hour, then reflux extraction twice for 0.5 hours each time, combine the extracts, and concentrate under reduced pressure below 50°C to form a thick paste.

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PUM

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Abstract

The present invention discloses a camellia flower total flavone medicine preparation, including oral preparation and injection preparation, in which the weight percentage content of camellia flower total flavone in camellia flower extract is greater than 70%, and said camellia flower total flavone is obtained by making the camellia flower undergo the processes of extraction, filtering, concentration, dissolving in hot water, centrifugal separation, ultrafiltration and purifying column treatment. Said invention can be used for curing angiocardiopathy and cerebrovascular disease, and can obtain good therapeutic effect.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to a pharmaceutical preparation of camellia total flavonoids, a preparation method and application thereof. technical background [0002] Coronary heart disease is one of the diseases that seriously endanger human health and have high morbidity and mortality. Research on the protective effect of traditional Chinese medicine on myocardial ischemia has been paid more and more attention, especially the flavonoids of various plants have been extensively studied. Camellia is also known as camellia, winter flower, datura. Camellia is sweet and cool in nature and bitter in taste. It is a good medicine for cooling blood, stopping bleeding, dispelling stasis, and reducing swelling. In Li Shizhen's "Compendium of Materia Medica", "Beautiful Prescriptions for No Medicine", "Saving the Sea of ​​Suffering", "Supplements to Compendium" and other ancient medical works, there are com...

Claims

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Application Information

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IPC IPC(8): A61K36/82A61P9/10
Inventor 魏海关
Owner 北京天新园医药科技开发有限公司
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