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Anticonsumption preparation and its new preparation method

A technology of preparations and traditional Chinese medicine preparations, applied in pill delivery, pharmaceutical formulations, antibacterial drugs, etc., can solve the problems of many impurities, affecting clinical application, and large doses

Inactive Publication Date: 2006-08-30
FUKANGREN BIO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But in practice, because the medicine is prepared by powdering the medicinal materials into the medicine, there are many impurities and large doses, which seriously affect its clinical application.

Method used

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  • Anticonsumption preparation and its new preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0070] The preparation method of dropping pill of the present invention:

[0071] prescription:

[0072] Aodi tea 450g Baibu 180g Morus alba bark 90g

[0073] Chuanposhi 180g Five Fingers Peach 180g White and 180g

[0074] PEG4000 100g

[0075] Makes 1000 pills

[0076] Preparation:

[0077] (1) Take the prescribed medicinal materials, add water to decoct 3 times, each time for 1 hour, combine the decoction, filter, the filtrate is concentrated to a certain volume, add 10 times the amount of 95% ethanol to mix, let stand for 12 hours, filter, the filtrate reduces Concentrate into a thick extract for later use;

[0078] (2) Add the above-mentioned extract, add the prescribed amount of PEG4000, put it into a container, heat and dissolve it, shake it to make it melt into a uniform solution, and put it into a liquid storage tank. Keep the dripping temperature at 80°C, and control the dripping speed, the condensate is liquid paraffin, and you can get it by dripping.

Embodiment 2

[0080] The preparation method of soft capsule of the present invention:

[0081] prescription:

[0082] Aodi Tea 1800g Baibu 720g Mulberry Bark 360g

[0083] Chuanposhi 720g Five Fingers Peach 720g White and 720g

[0084] PEG400 400g

[0085] Makes 1000 capsules

[0086] Preparation:

[0087] (1) Take the prescribed medicinal materials, add water to decoct 3 times, each time for 1 hour, combine the decoction, filter, the filtrate is concentrated to a certain volume, add 10 times the amount of 95% ethanol to mix, let stand for 12 hours, filter, the filtrate reduces Concentrate into a thick extract for later use;

[0088] (2) Add an appropriate amount of PEG400 to the extract obtained above, mix and mix evenly, and then add the remaining amount of PEG400 to obtain a medicinal solution. In addition, gelatin solution is prepared according to a certain prescription. Control suitable conditions, adjust the content weight, and obtain soft capsules in a soft capsule machine.

Embodiment 3

[0090] The preparation method of tablet of the present invention:

[0091] prescription:

[0092] Aodi tea 700g Baibu 280g Morus alba bark 140g

[0093] Chuanposhi 280g Five Fingers Peach 280g White and 280g

[0094] Makes 1000 pieces

[0095] Preparation:

[0096] (1) Take Baiji, add 5 times the amount of water and use ultrasonic extraction for 2 times, each time for 40 minutes, combine the extracts, filter, and concentrate the filtrate under reduced pressure to form a thick extract, set aside;

[0097] (2) Take the remaining medicinal materials, soak them with 75% ethanol for 40 minutes, then heat and reflux for extraction 3 times, each time for 1 hour, combine the extracts, concentrate under reduced pressure to form a thick paste, and set aside;

[0098] (3) Combine the above active ingredients, add 5.0 g of aspartame and 200.0 g of mannitol, granulate, dry, add 3.0 g of magnesium stearate, mix well, and compress into tablets to obtain 1000 tablets.

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Abstract

A composite Chinese medicine in the form of dripping pill and soft capsule for treating infiltrative pulmonary tuberculosis and blood-stained sputum, and its preparing process are disclosed.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine composition and a preparation process thereof, in particular to a prescription for infiltrating pulmonary tuberculosis with blood in sputum and a preparation process thereof. Background technique: [0002] For infiltrating pulmonary tuberculosis, blood in sputum is a common clinical symptom. Traditional Chinese medicine often adopts the methods of promoting blood circulation to stop bleeding, dispelling blood stasis and promoting regeneration, eliminating phlegm and relieving cough to treat it, and the curative effect is remarkable. Anti-tuberculosis pill is its representative drug. However, in practice, because the medicine is prepared by powdering the medicinal materials, it leads to many impurities and large doses, which seriously affects its clinical application. [0003] Compared with ordinary pills, the preparation prepared by the extraction process of the present invention can better coll...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61K9/00A61K9/06A61K9/20A61K9/48A61P31/06A61P11/00
Inventor 刘露
Owner FUKANGREN BIO PHARMA
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