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Chinese medicine extract for resisting AIDS virus and preparing method

An anti-AIDS and extract technology, applied in antiviral agents, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of large randomness, toxic side effects, and high development costs, and achieve stable effects and good repeatability. , the effect of stable inhibition

Inactive Publication Date: 2006-10-25
ZHEJIANG UNIV
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Problems solved by technology

At present, a safe and effective vaccine has not been successfully developed; the existing chemically synthesized anti-HIV drugs can only temporarily inhibit the replication of the virus, which has the disadvantages of large randomness, high development costs, easy drug resistance, and serious side effects , the international medical community began to pay attention to the research of ethnic medicine anti-HIV

Method used

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  • Chinese medicine extract for resisting AIDS virus and preparing method
  • Chinese medicine extract for resisting AIDS virus and preparing method

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Embodiment Construction

[0018] Further illustrate with specific embodiment below:

[0019] Fresh dry honeysuckle 630g, decoct in water for 1-1.5 hours, filter out the precipitate, concentrate the decoction to the extract, and get 3.767g of extract; collect the filtered precipitate, remove impurities with sheath alcohol, add HCL to acidify to PH 1.5, stir , precipitated solids, washed twice with 50% and 95% ethanol to obtain 3.886 g of powdery precipitates.

[0020] If the extract and precipitate are not used temporarily, they can be preserved in 95% alcohol.

[0021] Add a small amount of deionized water to the extract and the precipitate respectively, repeatedly bathe in 37°C water, vortex, seal with a parafilm, and place at room temperature overnight. The next day, deionized water was added gradually, and the water bath at 37°C was repeated. Seal with parafilm and let stand overnight at room temperature. On the third day, the dissolved extract and precipitate were filtered with a 0.45 μm disposa...

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Abstract

The present invention discloses a Chinese medicine extract for resisting acquired immunodeficiency syndrome (AIDS) virus and its preparation method. Said Chinese medicine extract is lonicera flower extract, and its preparation method includes the following steps: decocting lonicera flower in water, concentrating decoction to obtain extract, using acid to regulate pH value, filtering to remove impurity, collecting precipitate, using ethyl alcohol to wash said precipitate at twice, collecting granular precipitate, dissolving extract and granular precipitate, filtering and drying so as to obtain the invented product.

Description

technical field [0001] The invention belongs to the technical field of chemical traditional Chinese medicine, and relates to an anti-AIDS virus active ingredient of traditional Chinese medicine and a preparation method thereof. Background technique [0002] HIV (human immunodeficiency virus), human immunodeficiency virus, is the pathogen of AIDS. HIV mainly affects CD 4 + In the first few years of infection, the immune system can clear a large number of replicated viruses in time, and the infected person may not show any symptoms; as the course of the disease prolongs, CD 4 + The number of cells gradually decreases, and the immune system tends to collapse. When CD 4 + When the number of cells is as low as 200 / ml, infected people often die from a variety of serious opportunistic infections and tumors. Since the 1980s, HIV infection has spread rapidly worldwide, 95% of which occurred in developing countries. China entered a period of rapid growth around 1994, and accord...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/355A61K133/00A61P31/18
Inventor 吴南屏吴霞张小玲
Owner ZHEJIANG UNIV
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