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Injection for treating eperythrozoonosis of domestic animal and its prepn. method

A technology of eperythrozoonosis and injection, which is applied in the field of injections for the treatment of livestock eperythrozoonosis, can solve problems such as ineffective effects, and achieve the effects of definite curative effect, long duration of drug effect and accurate dosage

Inactive Publication Date: 2006-11-29
江西百思技术咨询有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, veterinary clinical treatment of Eperythrozoonosis generally uses drugs such as oxytetracycline, kanamycin sulfate, and sulfamethoxine sodium, but the effect is not obvious

Method used

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  • Injection for treating eperythrozoonosis of domestic animal and its prepn. method
  • Injection for treating eperythrozoonosis of domestic animal and its prepn. method
  • Injection for treating eperythrozoonosis of domestic animal and its prepn. method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Triazamidine 3g Doxycycline hydrochloride 3g Sodium sulfite 0.1g

[0017] Sodium EDTA 0.01g Glycerin 50g

[0018] The preparation method of the present invention: take the prescribed amount of triazine and doxycycline hydrochloride respectively, add 1 / 3 of the injection solvent glycerin, stir and dissolve; then add sodium sulfite and sodium edetate, stir and dissolve; Add 2 / 3 of the injection solvent glycerin, adjust the pH value, semi-finished product inspection, filtration, potting, sterilize at 100°C for 30 minutes, cooling, light inspection, printing, packaging, finished product inspection, storage, ready to get.

Embodiment 2

[0020] Triazamidine 1g Doxycycline hydrochloride 3g Sodium bisulfate 0.1g

[0021] Sodium edetate 0.01g Polyethylene glycol 80g

[0022] The preparation method of the present invention: take the prescription amount of triazamidine and doxycycline hydrochloride respectively, add 1 / 3 of the injection solvent polyethylene glycol, stir and dissolve; then add sodium bisulfite and ethylenediaminetetraacetic acid Sodium, stir to dissolve; add the remaining injection solvent polyethylene glycol, adjust the pH value, semi-finished product inspection, filter, potting, sterilize at 100°C for 30 minutes, cooling, light inspection, printing, packaging, finished product inspection, entry Library, that is.

Embodiment 3

[0024] Triazamidine 5g Doxycycline Hydrochloride 5g

[0025] Sodium metabisulfite 0.2g Sodium edetate 0.02g Propylene glycol 98g

[0026] The preparation method of the present invention: take the prescribed amount of triazamidine and doxycycline hydrochloride respectively, add 1 / 3 of the injection solvent propylene glycol, stir and dissolve; then add sodium metabisulfite and disodium edetate, stir and dissolve Add the remaining solvent for injection, propylene glycol, adjust the pH value, inspect the semi-finished product, filter, potting, sterilize at 100°C for 30 minutes, cool, inspect by light, print, pack, inspect the finished product, and put it into storage.

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Abstract

A liquid injection for treating the epierythrocyte disease of domestic animal is prepared from trinitroamidin, doxycycline, the additive chosen from sodium sulfite, sodium hydrogen sulfite, sodium pyrosulfite, etc, and the injection solvent chosen from polyethanediol, glycerine, propanediol, etc through sequentially dissolving in injection solvent while stirring, regulating pH value, filtering, sterilizing, cooling and examining.

Description

technical field [0001] The invention relates to an injection for treating livestock eperythrozoonosis and a preparation process thereof. Background technique [0002] Eperythrozoonosis is commonly known as erythroderma, also known as erythrozoonosis. In 1934, Adal first discovered Eperythrozoon Wennnerii in cattle, and then some people successively discovered different new species in sheep, pigs, cats, rabbits and other animals. Previously, these microorganisms were mistakenly considered as protozoa. After in-depth research by many people, it was found that the ultrastructure and metabolic characteristics were similar to those of Rickettsia, and it was listed in the order Rickettsia, Anaplasmaceae, and Eperythrocytosis. The occurrence of this disease has been reported all over the world. After 1982 in our country, there were reports of Eperythrozoon in Jiangsu and Hebei. , redness of the skin, jaundice of the eyes and oral mucosa, symptoms of anemia...

Claims

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Application Information

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IPC IPC(8): A61K31/655A61K31/65A61K47/04A61K47/18A61P33/00
Inventor 张克曾标其
Owner 江西百思技术咨询有限公司
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