Bacteriostatic externally applied preparation for treating gynecological inflammation and method for preparing same

A technology for external preparations and gynecological inflammation, applied in the field of external preparations and its preparation, can solve the problems of vaginal, urethral and anal cross-infection, single efficacy, toxic and side effects, etc., and achieve ideal therapeutic effect, rapid effect, and long-term effect

Inactive Publication Date: 2006-12-20
杨晋懿
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Vaginitis, cervicitis, and pelvic inflammatory disease are common diseases of women. At the same time, due to the special reasons of the physiological structure of women's genitals and vagina, women's genitals and vagina are easily infected with Staphylococcus aureus, Candida albicans and mold, Pseudomonas aeruginosa bacteria and Pseudomonas aeruginosa, Escherichia coli, saccharomyces, trichomonas, etc., so vaginitis, cervicitis, pelvic inflammatory disease, etc. are common problems in women's genitals and vagina, and the related treatments of these problems in the prior art have adopted other drugs such as antibiotics And other dosage forms, but the use of antibiotics will have certain toxic an

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0022] Example 1 of the present invention: Weigh 60g of raw materials of Sophora flavescens, 40g of rhubarb, 30g of Cnidium, 20g of cork, 20g of Smilax chinensis, 30g of white ringworm, 20g of sclerotium, 30g of wild chrysanthemum, 30g of senecio, 20g of Sichuan pepper, Crane louse 20g, evodia 20g, earth vitex bark 20g, gentian 30g, catechu 25g, angelica 30g, and Kochia scoparia 30g. After quick elutriation, it is decocted in a percolating tank for 2 times, the first time adding water is higher than The medicinal material is 5cm, decocted for 3 hours, the second time adding water just submerged the medicinal material, decocted for 2 hours, combined the decoction, filtered, and the filtrate was concentrated to 60℃. When the filtrate was concentrated to 60℃, the relative density was 1.02. Take up the supernatant and add water to 1500Kg to obtain a diluted drug solution. Take 30% of the diluted drug solution and add 10g of carbomer and 8g of triethanolamine and stir until completely ...

Example Embodiment

[0023]Example 2 of the present invention: Weigh the washed raw materials Sophora flavescens 60g, rhubarb 40g, Cnidium cnidium 30g, Cork 30g, Smilax glabra 60g, White ringworm 30g, Stemona 30g, Wild chrysanthemum 30g, Senecio 30g, Sichuan Pepper 30g, crane louse 20g, evodia 30g, wattle 30g, gentian 50g, catechu 45g, angelica 50g, Kochia scoparia 50g, after quick elutriation, place in a multifunctional extraction tank, add water to infiltrate, open the folder Heat the cover to boiling, decoc 3 times, add water 6cm above the medicinal material for the first time, decoc for 2 hours, add water for the second time just to submerge the medicinal material, decoc for 1.5 hours, add water for the third time just submerge the medicinal material, and cook for 1 hour. Combine the three decoctions, filter, and concentrate the filtrate to a clear ointment with a relative density of 1.02 when measured at 60°C. Add 10g of benzoic acid, clarifying agent, and purified water to 1500kg to obtain a dil...

Example Embodiment

[0024] Example 3 of the present invention: Weigh 10g of raw materials of Sophora flavescens, 10g of rhubarb, 10g of Cnidium, 10g of cork, 10g of sclerotium, 10g of white ringworm, 10g of sclerotium, 10g of wild chrysanthemum, 10g of senecio, 5g of Sichuan pepper, Crane louse 5g, evodia 5g, wattle bark 5g, gentian 10g, catechu 10g, angelica 10g, and Kochia scoparia 10g. After quick washing, put it in a soaking tank and decoct it for 2 times. The medicinal material is 3cm, decocted for 1 hour, the second time adding water just submerged the medicinal material, decocted for 1.5 hours, combined the decoction, filtered, and the filtrate was concentrated to 60℃. When the filtrate was concentrated to 60℃, the relative density was 1.02. Dissolve in medium heating, add the above-mentioned clear ointment after completely dissolving uniformly, stir evenly, inject molding, cooling, demoulding, and packaging to obtain suppository.

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Abstract

The invention relates to a Chinese pharmaceutical composition for treating gynaecologic inflammation and process for preparation, wherein the composition is prepared from flavescent sophora root, rhubarb horsetails, cnidium fruit, corktree bark, poria cocos, Chinese dittany bark, roor of sessile stemona, wild chrysanthemum flower, Senecio scandens, zanthoxylum piperitum, carpesium fruit, evodia rutaecarpa, cortex pseudolaricis, gentian root, black catechu, dahurian angelica root, broom cypress fruit, dried alum, borax, metronidazole and auxiliary materials.

Description

Technical field: [0001] The invention relates to an external preparation and a preparation method thereof, in particular to an external preparation for inhibiting bacteria and treating gynecological inflammation and a preparation method thereof, belonging to the technical field of antibacterial preparations. Background technique: [0002] Vaginitis, cervicitis, and pelvic inflammatory disease are common diseases of women. At the same time, due to the special reasons of the physiological structure of women's genitals and vagina, women's genitals and vagina are easily infected with Staphylococcus aureus, Candida albicans and mold, Pseudomonas aeruginosa bacteria and Pseudomonas aeruginosa, Escherichia coli, saccharomyces, trichomonas, etc., so vaginitis, cervicitis, pelvic inflammatory disease, etc. are common problems in women's genitals and vagina, and the related treatments of these problems in the prior art have adopted other drugs such as antibiotics And other dosage form...

Claims

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Application Information

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IPC IPC(8): A61K36/904A61K9/00A61K9/02A61P15/00A61P15/02A61P31/04A61P31/10A61P33/02A61K33/22A61K33/06A61K31/4164
Inventor 杨晋懿
Owner 杨晋懿
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